HIV 感染者的光学相干断层扫描血管造影评估视网膜微血管健康。
Assessment of retinal microvascular health by optical coherence tomography angiography among persons with HIV.
机构信息
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine.
Grady Healthcare System, Infectious Diseases Program.
出版信息
AIDS. 2021 Jul 1;35(8):1321-1324. doi: 10.1097/QAD.0000000000002890.
Abstract
Microvasculopathy may link HIV-related chronic inflammation and premature multimorbidity. In this proof-of-concept study, we used optical coherence tomography angiography (OCTA) to evaluate the retina as a convenient assessment of microvascular health among persons with HIV (PWH) undergoing surveillance ophthalmic care at Emory from 2018 to 2021. Among patients with longstanding HIV, OCTA identified microvascular abnormalities even among eyes without clinical retinal disease. Retinovascular evaluation by OCTA is a feasible, noninvasive technique for assessing microvasculopathy among PWH.
摘要
微血管病可能将 HIV 相关的慢性炎症与过早的多种合并症联系起来。在这项概念验证研究中，我们使用光相干断层扫描血管造影术（OCTA）来评估视网膜，作为在 2018 年至 2021 年期间在埃默里接受监测性眼科护理的 HIV 感染者（PWH）中评估微血管健康的一种便捷方法。在长期 HIV 感染者中，即使在没有临床视网膜疾病的眼中，OCTA 也能识别微血管异常。OCTA 对视网膜血管的评估是一种可行的、非侵入性的技术，可用于评估 PWH 的微血管病。
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