University of Alabama at Birmingham, Birmingham, AL.
Department of Urology, University of Alabama at Birmingham, Birmingham, AL.
Urology. 2021 Oct;156:e111-e113. doi: 10.1016/j.urology.2021.03.005. Epub 2021 Mar 21.
We report a rare case of newberyite (magnesium monohydrate phosphate trihydrate) urolithiasis in a young female with a past medical history significant for longstanding autoimmune hepatitis. She presented to the emergency department with newly diagnosed nephrolithiasis. Over the next 2 years, she had recurrent renal calculi and 3 urologic procedures. Notably, she did not have any history of urinary tract infections or genitourinary abnormalities. Her last stone analysis revealed the unusual combination of newberyite and ammonium acid urate. The pathophysiology of ammonium acid urate and newberyite stone formation as well as risk factors of development are discussed in this report.
我们报告了一例罕见的新贝里石(一水合磷酸镁三水合物)尿石症,患者为年轻女性,既往有长期自身免疫性肝炎病史。她因新发肾结石就诊于急诊科。在接下来的 2 年中,她反复出现肾结石,并接受了 3 次泌尿外科手术。值得注意的是,她没有尿路感染或泌尿生殖系统异常的病史。她最后一次的结石分析显示了新贝里石和尿酸铵的不寻常组合。本报告讨论了尿酸铵和新贝里石结石形成的病理生理学以及发病的危险因素。