Harrache D, Mesri A, Addou A, Semmoud A, Lacour B, Daudon M
Département de Chimie, Université de Sidi-Bel-Abbes, Algérie.
Ann Urol (Paris). 1997;31(2):84-8.
We analyzed a series of 61 stones from children aged 3 to 14 years old using Fourier transform infrared spectroscopy. The calculi were collected from urology departments of the University Hospitals of Oran, Sidi-Bel-Abbès and Mostaganem in West Algeria. This series is the first investigation concerning the composition of stones in children based on infrared analysis. Calculi were more frequent in males (75.4%) and mainly localized in the bladder (55.8%). Upper urinary tract calculi were more frequent in children over the age of 10 years, and the sex ratio was about 1. Calcium oxalate monohydrate was present in 70.5% of stones and was the main component in 50.8% of cases both in whole stones and nuclei. In contrast, calcium oxalate dihydrate was the main component in only 9.8% of calculi although it was present in 75.4% of stones. Ammonium urate was detected in 29.5% of stones and was always the main component of nuclei. Uric acid, observed in 31.1% of calculi, was the major constituent in 14.7% of stones and 19.7% of nuclei. Magnesium ammonium phosphate was observed in 24.6% of stones as a consequence of urinary tract infection by urea-splitting bacteria. Our observations emphasized that the anatomical location of stone and their composition were in accordance with those previously reported in other countries.
我们使用傅里叶变换红外光谱法分析了一系列来自3至14岁儿童的61颗结石。这些结石是从阿尔及利亚西部奥兰、西迪-贝勒-阿贝斯和莫斯塔加内姆大学医院的泌尿外科收集的。该系列是基于红外分析对儿童结石成分的首次调查。结石在男性中更为常见（75.4%），主要位于膀胱（55.8%）。上尿路结石在10岁以上儿童中更为常见，性别比约为1。一水草酸钙存在于70.5%的结石中，在50.8%的结石及结石核心中均为主要成分。相比之下，二水草酸钙仅在9.8%的结石中为主要成分，尽管它存在于75.4%的结石中。尿酸铵在29.5%的结石中被检测到，并且始终是结石核心的主要成分。尿酸在31.1%的结石中被观察到，是14.7%的结石及19.7%的结石核心中的主要成分。由于尿素分解细菌引起的尿路感染，磷酸镁铵在24.6%的结石中被观察到。我们的观察结果强调，结石的解剖位置及其成分与其他国家先前报道的一致。
