Departamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional - Unidad Mérida, Km. 6 Antigua Carretera a Progreso, CORDEMEX, CP 97310, Mérida, Yucatán, Mexico.
Unidad de Química Sisal, Facultad de Química, Universidad Nacional Autónoma de México, Puerto de Abrigo S/N, 97356, Sisal, Yucatán, Mexico.
Bull Environ Contam Toxicol. 2022 Jan;108(1):78-84. doi: 10.1007/s00128-021-03176-w. Epub 2021 Mar 23.
In this study, the genotoxic effect of contaminants was assessed through detection of DNA damage using the micronucleus (MNs) test in erythrocytes from 149 flounder fish collected in two regions of the Gulf of Mexico (GoM). The frequency of microcytes (MCs) was also evaluated in the same group of fish collected from the Perdido Foldbelt (PF) and the Yucatan Platform (YP). The MCs frequency was different among locations of the YP (p = 0.011), while MNs frequency varied among locations of PF (p = 0.024). MCs and MNs values correlated with heavy metals from fish muscle, fish species and localities. Mean number, prevalence, and intensity of MCs and MNs correlated with Al, PAHs, depth, and locality. MNs frequency showed a species-specific association (p = 0.004). MNs and MCs were associated with heavy metals and PAHs from fish muscle and sediments, and the MNs frequency was species dependent.
在这项研究中，通过微核（MNs）试验检测红细胞中的 DNA 损伤，评估了污染物的遗传毒性效应，该试验共涉及在墨西哥湾（GoM）的两个区域采集的 149 条比目鱼。还评估了同一组来自佩尔迪多褶皱带（PF）和尤卡坦台地（YP）的鱼的微细胞（MCs）频率。YP 不同地点的 MCs 频率存在差异（p = 0.011），而 PF 不同地点的 MNs 频率存在差异（p = 0.024）。MCs 和 MNs 的频率与鱼类肌肉中的重金属、鱼类物种和地点有关。MCs 和 MNs 的平均数量、流行率和强度与 Al、多环芳烃、深度和地点有关。MNs 频率与物种特异性有关（p = 0.004）。MNs 和 MCs 与鱼类肌肉和沉积物中的重金属和多环芳烃有关，且 MNs 频率取决于物种。
