State Key Laboratory of Pulp and Paper Engineering, School of Light Industry and Engineering, South China University of Technology, Guangzhou 510640, China.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China; Guangzhou New Chemical Material Technology Ltd., Guangzhou 510640, China.
Food Chem. 2021 Aug 30;354:129548. doi: 10.1016/j.foodchem.2021.129548. Epub 2021 Mar 17.
A low-cost and portable paper-based analytical device has been developed for high throughput and on-site monitoring TC residue in milk through visualized colorimetric reaction. The filtration and concentration effect induced by the porous nature of paper contribute to strengthen the color intensity, leading to quantitative and sensitive detection of tetracycline reaching 1 ppm detection limit, with the linear range of 1-100 ppm both in water and milk samples. The applicability was demonstrated by detection of TC in 18 different types of real milk samples with good recovery ranging from 88% to 113%. Furthermore, the dynamic degradation behavior of tetracycline was monitored through the device. To the best of our knowledge, this is the first report of colorimetric detection of tetracycline in milk using the paper-based device. This simple, fast, cost-effective (~$0.50 per device) and equipment-free paper-based platform provides a promising tool for future application in food and environmental safety.
已经开发出一种低成本、便携式的基于纸张的分析设备，用于通过可视化比色反应进行高通量和现场监测牛奶中的四环素残留。纸张的多孔性质引起的过滤和浓缩效果有助于增强颜色强度，从而实现对四环素的定量和敏感检测，达到 1ppm 的检测限，在水和牛奶样品中的线性范围为 1-100ppm。通过对 18 种不同类型的实际牛奶样品进行 TC 检测，证明了该方法的适用性，回收率在 88%至 113%之间。此外，还通过该设备监测了四环素的动态降解行为。据我们所知，这是首次使用基于纸张的设备对牛奶中的四环素进行比色检测的报道。这种简单、快速、经济实惠（每个设备约 0.50 美元）且无需设备的基于纸张的平台为未来在食品和环境安全领域的应用提供了有前途的工具。
