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在钙化和小股动脉行经导管主动脉瓣置换术中,外科切开术可避免血管并发症。

Surgical Cutdown Avoids Vascular Complications in Transcatheter Aortic Valve Replacement in Calcified and Small Femoral Arteries.

机构信息

Department of Cardiovascular Surgery, German Heart Centre Munich at the Technical University Munich, Munich, Germany.

Department of Cardiovascular Surgery, Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich at the Technical University of Munich, Munich, Germany.

出版信息

Thorac Cardiovasc Surg. 2022 Apr;70(3):199-204. doi: 10.1055/s-0041-1725202. Epub 2021 Mar 24.

Abstract

BACKGROUND

Third-generation transcatheter heart valves (THV) are predominantly implanted through a percutaneous, transfemoral access. To reduce vascular complications, we selectively performed surgical vascular access (cutdown) in patients with particular calcified or small femoral arteries. We aim to review our experience with this approach.

METHODS

All patients who underwent transfemoral transcatheter aortic valve replacement (TAVR) with a third-generation THV at our institution between March 2014 and April 2019 were included in the study. All available computerized tomography studies were reassessed for access vessel diameter and visual graduation of calcifications. Vascular complications are reported according to Valve Academic Research Consortium-2 criteria.

RESULTS

A total of 944 patients were included. Among them, 879 patients underwent a percutaneous access and 65 patients underwent surgical cutdown. Also, 459 Evolut R/PRO and 420 Sapien 3/ultra were implanted percutaneously and 40 Evolut R/PRO and 25 Sapien 3 were implanted with a surgical cutdown. Patients with surgical cutdown were older (80.0 ± 7.5 vs. 83.8 ± 7.5 years,  < 0.001), had smaller femoral arteries (8.0 ± 1.6 vs. 7.6 ± 1.6 mm,  = 0.034) and more severe vessel calcifications (17.5 vs. 1.0%,  < 0.001). Procedure time was similar for cutdown and percutaneous access (64.0 vs. 64.5 minutes,  = 0.879). With percutaneous access, 80 major vascular complications (10%) occurred, whereas with surgical cutdown, no major vascular complications occurred ( < 0.005). No wound infection occurred after surgical cutdown. The mean length of stay was 8 days in both groups.

CONCLUSION

Surgical cutdown for vascular access avoids vascular complications in patients with small or severely calcified femoral arteries.

摘要

背景

第三代经导管心脏瓣膜(THV)主要通过经皮、经股途径植入。为了减少血管并发症,我们在股动脉有特定钙化或较小的患者中选择性地进行手术血管入路(切开)。我们旨在回顾我们的经验。

方法

本研究纳入了 2014 年 3 月至 2019 年 4 月期间在我院接受第三代 THV 经股主动脉瓣置换术(TAVR)的所有患者。所有可获得的计算机断层扫描研究均重新评估了入路血管直径和钙化的视觉分级。血管并发症根据 Valve Academic Research Consortium-2 标准报告。

结果

共纳入 944 例患者。其中 879 例经皮入路,65 例经手术切开。此外,459 例 Evolut R/PRO 和 420 例 Sapien 3/ultra 经皮植入,40 例 Evolut R/PRO 和 25 例 Sapien 3 经手术切开。手术切开组患者年龄较大(80.0±7.5 岁比 83.8±7.5 岁, < 0.001),股动脉较小(8.0±1.6 毫米比 7.6±1.6 毫米, = 0.034),血管钙化更严重(17.5%比 1.0%, < 0.001)。切开组和经皮组的手术时间相似(64.0 分钟比 64.5 分钟, = 0.879)。经皮入路发生 80 例重大血管并发症(10%),而手术切开组无重大血管并发症( < 0.005)。手术切开组无伤口感染。两组平均住院时间均为 8 天。

结论

对于股动脉小或严重钙化的患者,手术切开血管入路可避免血管并发症。

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