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垂体漏斗部表皮样囊肿:垂体功能减退的罕见病因。

Pituitary infundibular epidermoid cyst: a rare cause of hypopituitarism.

作者信息

Ahmad Sajjad, Surya Ashutosh, Hayhurst Caroline, Davies Stephen

机构信息

Department of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, Cardiff, UK

Department of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, Cardiff, UK.

出版信息

BMJ Case Rep. 2021 Mar 24;14(3):e241065. doi: 10.1136/bcr-2020-241065.

Abstract

A 53-year-old man presented with 6 months history of weight loss associated with nausea, fatigue, dizziness and headache. On arrival he was in adrenal crisis. Biochemistry revealed anterior hypopituitarism with low cortisol, thyroxine, testosterone and a slightly raised prolactin. He was commenced on steroids, thyroxine and testosterone. MRI pituitary gland was reported to have a 9.4 mm microadenoma. Cabergoline was started for a possible microprolactinoma. Follow-up MRI showed increase in the size of complex cystic lesion causing chiasmal compression raising a possibility of craniopharyngioma. Visual fields assessment was normal. In view of the rapid enlargement, to protect vision and obtain a tissue diagnosis he underwent endoscopic trans-sphenoidal surgery. A cystic lesion was noted intraoperatively originating from pituitary stalk with intrasellar and suprasellar extension. It was filled with white caseous material and fluid. Histology revealed epidermoid cyst. His headache resolved postoperatively.

摘要

一名53岁男性,有6个月体重减轻病史,伴有恶心、乏力、头晕和头痛。入院时处于肾上腺危象。生化检查显示垂体前叶功能减退,皮质醇、甲状腺素、睾酮水平低,催乳素略有升高。开始给予类固醇、甲状腺素和睾酮治疗。据报告,垂体MRI显示有一个9.4毫米的微腺瘤。开始使用卡麦角林治疗可能的微泌乳素瘤。随访MRI显示复杂囊性病变大小增加,导致视交叉受压,增加了颅咽管瘤的可能性。视野评估正常。鉴于病变迅速增大,为保护视力并获得组织诊断,他接受了内镜经蝶窦手术。术中发现一个囊性病变,起源于垂体柄,向鞍内和鞍上延伸。囊内充满白色干酪样物质和液体。组织学检查显示为表皮样囊肿。术后他的头痛症状缓解。

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Infundibular Epidermoid Cyst: Case Report and Systematic Review.漏斗部表皮样囊肿:病例报告和系统评价。
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本文引用的文献

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Infundibular Epidermoid Cyst: Case Report and Systematic Review.漏斗部表皮样囊肿:病例报告和系统评价。
World Neurosurg. 2019 Oct;130:110-114. doi: 10.1016/j.wneu.2019.06.205. Epub 2019 Jul 5.
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Surgical treatment of intracranial epidermoid tumors.颅内表皮样囊肿的外科治疗
Neurol Med Chir (Tokyo). 2003 Jun;43(6):275-80; discussion 281. doi: 10.2176/nmc.43.275.

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