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三种通气模式对冠状动脉旁路移植术患者的影响:一项随机临床试验。

Effects of three pulmonary ventilation regimes in patients undergoing coronary artery bypass graft surgery: a randomized clinical trial.

机构信息

Department of Physiotherapy, Kasturba Medical College, Manipal Academy of Higher Education, Bejai, Mangalore, 575004, India.

Department of Physiotherapy, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.

出版信息

Sci Rep. 2021 Mar 24;11(1):6730. doi: 10.1038/s41598-021-86281-4.

Abstract

The aim was to compare the effect of diaphragmatic breathing exercise (DBE), flow- (FIS) and volume-oriented incentive spirometry (VIS) on pulmonary function- (PFT), functional capacity-6-Minute Walk Test (6 MWT) and Functional Difficulties Questionnaire (FDQ) in subjects undergoing Coronary Artery Bypass Graft surgery (CABG). The purpose of incorporating pulmonary ventilator regimes is to improve ventilation and avoid post-operative pulmonary complications. CABG patients (n = 72) were allocated to FIS, VIS and DBE groups (n = 24 each) by block randomization. Preoperative and postoperative values for PFT were taken until day 7 for all three groups. On 7th postoperative day, 6 MWT and FDQ was analyzed using ANOVA and post-hoc analysis. PFT values were found to be decreased on postoperative day 1(Forced Vital Capacity (FVC) = FIS group-65%, VIS group-47%, DBE group-68%) compared to preoperative day (p < 0.001). PFT values for all 3 groups recovered until postoperative day 7 (FVC = FIS group-67%, VIS group-95%, DBE group-59%) but was found to reach the baseline in VIS group (p < 0.001). When compared between 3 groups, statistically significant improvement was observed in VIS group (p < 0.001) in 6 MWT and FDQ assessment. In conclusion, VIS was proven to be more beneficial in improving the pulmonary function (FVC), functional capacity and FDQ when compared to FIS and DBE.

摘要

目的是比较膈肌呼吸运动(DBE)、流量(FIS)和容量导向激励性肺活量计(VIS)对行冠状动脉旁路移植术(CABG)患者的肺功能(PFT)、6 分钟步行测试(6MWT)和功能困难问卷(FDQ)的影响。纳入肺呼吸机方案的目的是改善通气并避免术后肺部并发症。CABG 患者(n=72)按区组随机分为 FIS、VIS 和 DBE 组(每组 n=24)。三组患者均于术前和术后第 7 天进行 PFT 检测。术后第 7 天,采用 ANOVA 和事后分析比较三组患者的 6MWT 和 FDQ。与术前相比,三组患者术后第 1 天的 PFT 值均降低(FVC:FIS 组 65%、VIS 组 47%、DBE 组 68%)(p<0.001)。三组患者的 PFT 值在术后第 7 天恢复(FVC:FIS 组 67%、VIS 组 95%、DBE 组 59%),但在 VIS 组恢复至基线水平(p<0.001)。三组患者比较时,VIS 组在 6MWT 和 FDQ 评估中,肺功能(FVC)、功能能力和 FDQ 的改善具有统计学意义(p<0.001)。总之,与 FIS 和 DBE 相比,VIS 更有利于改善肺功能(FVC)、功能能力和 FDQ。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9887/7990944/0d6ff7aecbad/41598_2021_86281_Fig1_HTML.jpg

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