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用芬戈莫德治疗的多发性硬化症患者的迟发性黄斑水肿

Late Onset Macular Oedema in a Patient with Multiple Sclerosis Treated with Fingolimod.

作者信息

Camós-Carreras Anna, Alba-Arbalat Salut, Dotti-Boada Marina, Parrado-Carrillo Alba, Bernal-Morales Carolina, Saiz Albert, Sánchez-Dalmau Bernardo

机构信息

Ophthalmology Department, Hospital Clinic de Barcelona, Barcelona, Spain.

Neurology Department, Hospital Clinic de Barcelona, Barcelona, Spain.

出版信息

Neuroophthalmology. 2020 Oct 6;45(1):61-64. doi: 10.1080/01658107.2020.1821065. eCollection 2021.

DOI:10.1080/01658107.2020.1821065
PMID:33762792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7946040/
Abstract

Macular oedema is a rare complication of fingolimod treatment. It usually presents within 3-4 months, but occasionally presents later. It can resolve without treatment despite continuation of fingolimod treatment. Herein we report a case of very late onset macular oedema in a 49-year-old woman with multiple sclerosis treated with fingolimod for 7 years. The patient presented with blurred vision in both eyes with visual acuities of 20/32 in her right eye and 20/25 in her left eye. She had macular oedema, that without discontinuing fingolimod treatment, resolved after 1 month.

摘要

黄斑水肿是芬戈莫德治疗的一种罕见并发症。它通常在3 - 4个月内出现,但偶尔也会在更晚的时候出现。尽管继续使用芬戈莫德治疗,它仍可在未经治疗的情况下自行消退。在此,我们报告一例49岁患有多发性硬化症的女性,使用芬戈莫德治疗7年后出现非常迟发性黄斑水肿的病例。该患者双眼视力模糊,右眼视力为20/32,左眼视力为20/25。她患有黄斑水肿,在未停用芬戈莫德治疗的情况下,1个月后水肿消退。

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Real-world incidence of fingolimod-associated macular oedema.现实世界中芬戈莫德相关黄斑水肿的发生率。
Mult Scler Relat Disord. 2020 Jul;42:102125. doi: 10.1016/j.msard.2020.102125. Epub 2020 Apr 28.
2
Fingolimod-associated macular edema controlled with nepafenac non-steroidal anti-inflammatory opthalmologic applications.用奈帕芬胺非甾体抗炎眼科制剂控制的芬戈莫德相关性黄斑水肿
Clin Mol Allergy. 2020 Mar 12;18:3. doi: 10.1186/s12948-020-00119-4. eCollection 2020.
3
LETTER TO THE EDITOR Screening for Fingolimod Associated Macular Oedema: Experience Versus Guidelines.致编辑的信:芬戈莫德相关性黄斑水肿的筛查:经验与指南
Open Ophthalmol J. 2014 Oct 3;8:73-4. doi: 10.2174/1874364101408010073. eCollection 2014.
4
Successful treatment of fingolimod-associated macular edema with intravitreal triamcinolone with continued fingolimod use.使用玻璃体内曲安奈德成功治疗与芬戈莫德相关的黄斑水肿,并继续使用芬戈莫德。
Mult Scler. 2015 Feb;21(2):249-51. doi: 10.1177/1352458514528759. Epub 2014 Apr 2.
5
Management of fingolimod-associated macular edema.芬戈莫德相关黄斑水肿的管理。
JAMA Ophthalmol. 2013 May;131(5):694-6. doi: 10.1001/jamaophthalmol.2013.47.
6
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7
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