Gaskin Jennifer Chen-Chia Fan, Coote Michael
Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.
BMJ Case Rep. 2015 May 12;2015:bcr2015210415. doi: 10.1136/bcr-2015-210415.
We describe the first case of fingolimod-associated bilateral cystoid macular oedema (CMO) following uncomplicated cataract surgery. A 57-year-old woman has been on fingolimod for the past 2 years for the treatment of relapsing-remitting multiple sclerosis. She underwent uneventful consecutive cataract surgery 2 weeks apart. Three weeks following the second cataract operation, she reported gradual-onset blurred vision bilaterally. Examination revealed mildly reduced visual acuity and bilateral CMO. Treatment with topical corticosteroids and non-steroidal anti-inflammatory eye drops, as well as cessation of fingolimod in collaboration with the neurologist, resulted in complete resolution of the CMO. Patients on fingolimod are likely to be at increased risk of developing postoperative CMO.
我们描述了首例在白内障手术无并发症后出现的与芬戈莫德相关的双侧黄斑囊样水肿（CMO）病例。一名57岁女性在过去2年中一直服用芬戈莫德治疗复发缓解型多发性硬化症。她在相隔2周的时间里顺利接受了连续两次白内障手术。第二次白内障手术后3周，她报告双侧视力逐渐模糊。检查发现视力轻度下降及双侧CMO。局部使用皮质类固醇和非甾体抗炎眼药水治疗，并与神经科医生合作停用芬戈莫德，结果CMO完全消退。服用芬戈莫德的患者术后发生CMO的风险可能会增加。
