Biglow Layana R, Cuda Jonathan, Dotson Jennifer
Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Pathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Cureus. 2021 Feb 18;13(2):e13424. doi: 10.7759/cureus.13424.
Malignant peripheral nerve sheath tumors are rare soft tissue sarcomas that are often associated with neurofibromatosis type-1. These tumors share common immunohistochemistry findings which can make diagnosis difficult. We present the case of a woman who presented with a diagnosis of metastatic melanoma of the index finger of her left hand but was eventually diagnosed with primary epithelioid malignant peripheral nerve sheath tumor. We will be highlighting the diagnostic challenge of differentiating between these two very different malignancies.
恶性外周神经鞘瘤是一种罕见的软组织肉瘤，常与1型神经纤维瘤病相关。这些肿瘤具有共同的免疫组化表现，这可能使诊断变得困难。我们报告了一例女性病例，该患者最初被诊断为左手食指转移性黑色素瘤，但最终被诊断为原发性上皮样恶性外周神经鞘瘤。我们将重点强调鉴别这两种截然不同的恶性肿瘤所面临的诊断挑战。
