Zapata Laguado Martin, Canales Pacheco Eduardo Luis, Sanchez Castillo Jesus Oswaldo
Clinical Oncology, Universidad el Bosque/Instituto Nacional de Cancerología, Bogota, COL.
General Medicine, Universidad del Magdalena/Instituto Nacional de Cancerología, Bogota, COL.
Cureus. 2021 Feb 19;13(2):e13439. doi: 10.7759/cureus.13439.
Adamantinoma of long bones is a slow-growing, low-grade primary malignant bone tumor. It is a rare entity and accounts for less than 1% of all primary bone tumors, and in most cases, it occurs in the mid-axis of the tibia of adolescents and young adults. In this report, we describe the case of a 53-year-old woman with a diagnosis of adamantinoma of the left tibia who was initially treated surgically in 2004. Two years later, she presented with local relapse, for which she underwent new surgical management. The patient was referred to our practice 16 years after the initial diagnosis, and she presented with recurrence characterized by ipsilateral inguinal lymph node metastasis. The histological findings and immunohistochemistry were compatible with metastatic adamantinoma with high-grade differentiation, which ultimately required surgical salvage management.
长骨造釉细胞瘤是一种生长缓慢、低级别原发性恶性骨肿瘤。它是一种罕见的疾病,占所有原发性骨肿瘤的比例不到1%,在大多数情况下,发生于青少年和年轻成年人胫骨的中轴部位。在本报告中,我们描述了一例53岁女性患者,诊断为左胫骨造釉细胞瘤,2004年最初接受了手术治疗。两年后,她出现局部复发,为此接受了新的手术治疗。在初次诊断16年后,该患者转诊至我们的科室,她出现了以同侧腹股沟淋巴结转移为特征的复发。组织学检查结果和免疫组化结果与高级别分化的转移性造釉细胞瘤相符,最终需要进行挽救性手术治疗。