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一名肝移植患者出现类圆线虫和钩虫合并感染。

Strongyloides and hookworms co-infection in a liver transplant patient.

作者信息

Alibrahim Fatimah, AlAlwan Abduljaleel, Al Thiab Khalefa, Alawaji Ahmad, Alwan Bassam, Taher Leena, Bosaeed Mohammad

机构信息

Infectious Disease Division, Department of Internal Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Department of Hepatobiliary Sciences and Organ Transplant Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

出版信息

IDCases. 2021 Mar 10;24:e01060. doi: 10.1016/j.idcr.2021.e01060. eCollection 2021.

Abstract

We here present a female patient who is a recipient of liver transplantation from a cadaveric donor. She developed abdominal pain, nausea, vomiting, and diarrhea for two weeks of duration, after four months of the transplant. Upper gastrointestinal (GI) endoscopy and stool analysis for ova and parasite showed Necator americanus / Ancylostoma duodenale (Hookworm) ova /larvae and Larvae. She had a dramatic clinical response to Ivermectin and Albendazole combination, which was given until the clearance of her stool exam. She was discharged from the hospital in good condition, and her infection is considered as a donor-derived transmission of these parasites. To the best of our knowledge, this is the first case report of and hookworm co-infection in a liver transplant patient. Parasitic infection should be considered in the differential diagnosis of diarrheal illness of cadaveric transplant patients, even if it is not prevalent in the region.

摘要

我们在此报告一名接受尸体供体肝脏移植的女性患者。移植四个月后,她出现了持续两周的腹痛、恶心、呕吐和腹泻。上消化道内镜检查以及粪便虫卵和寄生虫分析显示美洲板口线虫/十二指肠钩口线虫(钩虫)虫卵/幼虫。她对伊维菌素和阿苯达唑联合用药有显著的临床反应,用药直至粪便检查转阴。她康复出院,其感染被认为是这些寄生虫的供体源性传播。据我们所知,这是首例肝脏移植患者感染和钩虫共感染的病例报告。即使在该地区并不常见,尸体移植患者出现腹泻性疾病时,鉴别诊断中也应考虑寄生虫感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba0/7973314/3a27126560a5/gr1.jpg

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