Division of Gastroenterology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryo-Cho, Aoba-Ku, Sendai, Miyagi, 980-8574, Japan.
Division of Surgery, Tohoku University Hospital, 1-1, Seiryo-Cho, Aoba-Ku, Sendai, Miyagi, 980-8574, Japan.
Clin J Gastroenterol. 2021 Aug;14(4):1186-1190. doi: 10.1007/s12328-021-01346-1. Epub 2021 Mar 24.
A 66-year-old man with a history of diabetes and dilated cardiomyopathy underwent the implantation of a ventricular assist device (VAD) at the age of 62. He suffered from epigastralgia for a month and then visited our hospital with complaints of severe epigastralgia and hematemesis. A physical examination revealed abdominal distension without rigidity. Laboratory data showed severe systemic inflammation, multiple organ failure, and disseminated intravascular coagulation. Computed tomography showed multifocal thickness of the gastroduodenal wall with surrounding panniculitis, gas in a portal vein and a perigastric vein. Emergency esophago-gastro duodenoscopy (EGD) demonstrated a large erosion in the antrum of the stomach, and penetration surrounded by circumferentially ischemic mucosa in the second and third portions of the duodenum. Based on informed consent, conservative therapy was performed, and his condition improved enabling the start of oral intake on the 37th hospital day. However, 7 days later, there was a relapse of epigastralgia after a meal. Gastrointestinal series and EGD revealed a 10-mm-long pinhole-like stricture at the site. After laparoscopic gastro-jejunal bypass surgery, he has remained in a good condition for 2 years. We demonstrated a rare case of penetration due to severe ischemic duodenitis 4 years after VAD implantation.
一位 66 岁男性,有糖尿病和扩张型心肌病病史,于 62 岁时植入心室辅助装置(VAD)。他因上腹疼痛病史 1 个月,随后以严重的上腹疼痛和呕血为主诉就诊于我院。体格检查发现腹胀,无肌紧张。实验室数据显示严重的全身炎症、多器官衰竭和弥散性血管内凝血。计算机断层扫描显示胃十二指肠壁多处厚度增加,伴有周围脂膜炎、门静脉和胃周静脉积气。急诊食管胃十二指肠镜(EGD)显示胃窦部有大的溃疡,在十二指肠第二和第三部分有穿透性溃疡,周围环绕着环形缺血性黏膜。在获得知情同意后,进行了保守治疗,他的病情改善,在住院第 37 天开始口服饮食。然而,7 天后,餐后再次出现上腹疼痛。胃肠造影和 EGD 显示在该部位有 10mm 长的针孔样狭窄。在腹腔镜胃空肠旁路手术后,他的状况良好,已经持续了 2 年。我们展示了一例罕见的 VAD 植入后 4 年发生严重缺血性十二指肠炎导致穿透性溃疡的病例。