Department of Family Medicine, Seoul National University Hospital, Seoul National University School of Medicine, Seoul, Korea.
Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Eur J Cancer Care (Engl). 2021 Sep;30(5):e13443. doi: 10.1111/ecc.13443. Epub 2021 Mar 25.
To investigate factors associated with influenza vaccination in cancer survivors.
Study subjects were 1,945 Korean adult cancer survivors. Through medical record review and self-administered questionnaires, social and medical information was collected. Influenza vaccination was defined as ever having received a flu vaccine between one year before cancer diagnosis and the survey date. Multiple logistic regression analysis was used to evaluate factors associated with influenza vaccination.
Overall, 60.8% of study subjects had received an influenza vaccination. Younger survivors had a significantly lower vaccination rate than did the elderly survivors (80.22% vs. 54.73%). In younger survivors, longer time elapsed since cancer diagnosis, lifestyle modification counselling during cancer treatment, adequate physical exercise (≥150 min/week) and complementary medication use were positively associated with vaccination, whereas extra-pulmonary cancers, multimodality (≥3) cancer treatment and higher educational achievement were inversely associated. In elderly survivors, fewer factors had a positive (adequate physical exercise) or inverse (multimodality cancer treatment and current smoking) association with influenza vaccination.
Influenza vaccination rate was suboptimal, especially among younger cancer survivors. Targeted strategies are necessary to improve influenza vaccination in cancer survivors with consideration of individual characteristics such as age, lifestyle, cancer treatment modality, cancer type and education level.
调查癌症幸存者中与流感疫苗接种相关的因素。
研究对象为 1945 名韩国成年癌症幸存者。通过病历回顾和自我管理问卷收集社会和医疗信息。流感疫苗接种定义为在癌症诊断前一年至调查日期之间曾接种过流感疫苗。采用多因素 logistic 回归分析评估与流感疫苗接种相关的因素。
总体而言，60.8%的研究对象接种了流感疫苗。年轻的幸存者接种疫苗的比例明显低于老年幸存者（80.22%比 54.73%）。在年轻的幸存者中，癌症诊断后时间延长、癌症治疗期间的生活方式改变咨询、充足的体育锻炼（≥150 分钟/周）和补充药物使用与接种呈正相关，而非肺部癌症、多模式（≥3 种）癌症治疗和较高的教育程度则呈负相关。在老年幸存者中，较少的因素与流感疫苗接种呈正相关（充足的体育锻炼）或负相关（多模式癌症治疗和当前吸烟）。
流感疫苗接种率不理想，尤其是在年轻的癌症幸存者中。需要采取有针对性的策略，根据年龄、生活方式、癌症治疗方式、癌症类型和教育水平等个体特征，提高癌症幸存者的流感疫苗接种率。
