Frohner K, Kaltenbrunner W, Laufer G, Laczkovics A, Wolner E, Steinbach K
3. Medizinische Abteilung, Ludwig Boltzmann-Institut für Arrhythmieforschung, Wilhelminenspital, Wien.
Wien Klin Wochenschr. 1988 Mar 18;100(6):167-73.
5 patients (3 with coronary artery disease and chronic myocardial infarction, 2 with dilatative cardiomyopathy) with a mean age of 59 years (range 54-69 years) with drug refractory ventricular tachycardia and/or ventricular fibrillation received the automatic implantable cardioverter defibrillator (AICD). Intraoperative testing revealed a mean defibrillation threshold of 13 +/- 2.7 Joule. Over a mean follow-up period of 15.2 months (range 3-25 months) the patients received a total of 117 discharges. 15% of the delivered shocks were recorded during continuous ECG monitoring, 13% were associated with palpitations and 27% were discharged during syncope. 45% of shocks occurred in the absence of symptoms. No patient died suddenly. 1 patient died of intractable heart failure, 1 patient died of septic shock. In carefully selected patients the automatic implantable cardioverter defibrillator is an effective tool in the treatment of life-threatening ventricular tachyarrhythmias. Modifications of the device to incorporate programmability of the cut-off rate, the sensing criteria and the levels of shock energy, as well as the options for different pacing modes combined with memory functions are needed to improve antiarrhythmic strategies.
5例平均年龄59岁(范围54 - 69岁)、药物难治性室性心动过速和/或心室颤动患者(3例患有冠状动脉疾病和慢性心肌梗死,2例患有扩张型心肌病)接受了植入式自动心脏复律除颤器(AICD)治疗。术中测试显示平均除颤阈值为13±2.7焦耳。在平均15.2个月(范围3 - 25个月)的随访期内,患者共接受了117次电击。15%的电击是在连续心电图监测期间记录到的,13%与心悸有关,27%是在晕厥期间放电的。45%的电击发生时无症状。无患者猝死。1例死于顽固性心力衰竭,1例死于感染性休克。在精心挑选的患者中,植入式自动心脏复律除颤器是治疗危及生命的室性快速心律失常的有效工具。需要对该设备进行改进,以纳入截断率、感知标准和电击能量水平的可编程性,以及结合记忆功能的不同起搏模式选项,以改善抗心律失常策略。