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[犊牛接种抗大肠杆菌病疫苗后凝集素的动态变化]

[Dynamics of agglutinins following vaccination against coli-bacteriosis in calves].

作者信息

Penev P D

出版信息

Vet Med Nauki. 1977;14(5):13-8.

PMID:337649
Abstract

A bivalent vaccine, produced with strains Escherichia coli 078 and 0117 to control colibacteriosis in calves, was used to vaccinate experimentally 20 cows following up the agglutinin dynamics in the serum of calves born later on. It was found that the agglutinin titers of the 0 antibodies were lower than those of OK, and varied within the range of from 1:10 to 1:320, the titers of 1:20-1:40 values being prevalent. Highest level of titers was observed by the third day following birth. OK antibodies had titers that were 1-2 degrees higher, reaching their peak level as early as the 12-15 hour after birth. They persisted for a longer period in the blood serum of calves. The antibodies produced after vaccination were shown to be sensitive to 2-mercaptoethanol.

摘要

一种用大肠杆菌078和0117菌株生产的二价疫苗,用于预防犊牛大肠杆菌病,对20头母牛进行了实验性接种,随后观察所产犊牛血清中凝集素的动态变化。结果发现,O抗体的凝集素效价低于OK抗体,效价范围在1:10至1:320之间,以1:20 - 1:40的效价最为普遍。出生后第三天观察到最高效价水平。OK抗体的效价高1 - 2个滴度,早在出生后12 - 15小时就达到峰值水平。它们在犊牛血清中持续时间更长。接种疫苗后产生的抗体对2 - 巯基乙醇敏感。

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