MMWR Morb Mortal Wkly Rep. 2021 Mar 26;70(12):421-426. doi: 10.15585/mmwr.mm7012a3.
In 2018, an estimated 1.8 million persons living in Nigeria had HIV infection (1.3% of the total population), including 1.1 million (64%) who were receiving antiretroviral therapy (ART) (1). Effective ART reduces morbidity and mortality rates among persons with HIV infection and prevents HIV transmission once viral load is suppressed to undetectable levels (2,3). In April 2019, through the U.S. President's Emergency Plan for AIDS Relief (PEPFAR),* CDC launched an 18-month ART Surge program in nine Nigerian states to rapidly increase the number of persons with HIV infection receiving ART. CDC analyzed programmatic data gathered during March 31, 2019-September 30, 2020, to describe the ART Surge program's progress on case finding, ART initiation, patient retention, and ART Surge program growth. Overall, the weekly number of newly identified persons with HIV infection who initiated ART increased approximately eightfold, from 587 (week ending May 4, 2019) to 5,329 (week ending September 26, 2020). The ART Surge program resulted in 208,202 more HIV-infected persons receiving PEPFAR-supported ART despite the COVID-19 pandemic (97,387 more persons during March 31, 2019-March 31, 2020 and an additional 110,815 persons during April 2020-September 2020). Comprehensive, data-guided, locally adapted interventions and the use of incident command structures can help increase the number of persons with HIV infection who receive ART, reducing HIV-related morbidity and mortality as well as decreasing HIV transmission.
2018 年,尼日利亚估计有 180 万人感染艾滋病毒(占总人口的 1.3%),其中 110 万人(64%)正在接受抗逆转录病毒治疗(ART)(1)。有效的 ART 可降低艾滋病毒感染者的发病率和死亡率,并在病毒载量被抑制到无法检测的水平时防止艾滋病毒传播(2,3)。2019 年 4 月,通过美国总统艾滋病紧急救援计划(PEPFAR),* 疾病预防控制中心在尼日利亚的 9 个州启动了为期 18 个月的抗逆转录病毒治疗激增计划,以迅速增加感染艾滋病毒的人数接受 ART。疾病预防控制中心分析了 2019 年 3 月 31 日至 2020 年 9 月 30 日期间收集的项目数据,以描述抗逆转录病毒治疗激增计划在病例发现、开始抗逆转录病毒治疗、患者保留和抗逆转录病毒治疗激增计划增长方面的进展。总体而言,新发现的开始接受抗逆转录病毒治疗的艾滋病毒感染者每周人数增加了约 8 倍,从 2019 年 5 月 4 日(第 5 周)的 587 人增加到 2020 年 9 月 26 日(第 39 周)的 5329 人。尽管发生了 COVID-19 大流行,但抗逆转录病毒治疗激增计划仍使 208202 名更多感染艾滋病毒的人接受了 PEPFAR 支持的抗逆转录病毒治疗(2019 年 3 月 31 日至 3 月 31 日期间增加了 97387 人,2020 年 4 月至 2020 年 9 月期间又增加了 110815 人)。全面、以数据为指导、因地制宜的干预措施和使用事件指挥结构可以帮助增加接受抗逆转录病毒治疗的艾滋病毒感染者人数,降低与艾滋病毒相关的发病率和死亡率,并减少艾滋病毒传播。