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甲真菌病的简易诊断工具:甲下真菌镜检。

Onychoscopy: a quick and effective tool for diagnosing onychomycosis in a resource-poor setting.

机构信息

Department of Dermatology, Venereology, and Leprosy, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Department of Dermatology, Venereology, and Leprosy, Himalayan Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

出版信息

Acta Dermatovenerol Alp Pannonica Adriat. 2021 Mar;30(1):11-14.

Abstract

INTRODUCTION

Onychomycosis is the most prevalent nail disease. Although clinical diagnosis of onychomycosis is easy, fungal culture as a confirmatory test requires an equipped laboratory and is time-consuming. Onychoscopy is a simple, quick, and inexpensive technique and may help clinicians increase the diagnostic accuracy of onychomycosis. The aim of this study was to identify common onychoscopic patterns of onychomycosis and correlate them with clinical subtypes of onychomycosis.

METHODS

This study was performed in the dermatology outpatient department of a tertiary care hospital in northern India for 6 months. Clinically diagnosed cases of onychomycosis were confirmed by potassium hydroxide (KOH) mount. After obtaining informed written consent, these patients underwent onychoscopy with DermLite II hybrid m, 3Gen, polarized mode, 10× magnification. The common onychoscopic patterns were recorded and the data analyzed.

RESULTS

The study included 60 confirmed cases of onychomycosis. The common onychoscopic patterns observed were jagged edges with spikes of the onycholytic area in 65.5% of cases, longitudinal striae in 77.6%, distal irregular termination or a "ruin pattern" in 82.7%, and chromonychia in 62.1%. Clinical types of onychomycosis showed a statistically significant association with chromonychia (p = 0.000), jagged edges with spikes (p = 0.015), and distal irregular termination (p = 0.016).

CONCLUSIONS

Onychoscopy can be a complementary tool in clinical diagnosis of onychomycosis to alleviate the need for direct microscopy and culture.

摘要

简介

甲真菌病是最常见的指甲疾病。虽然临床诊断甲真菌病很容易,但真菌培养作为一种确认试验需要配备实验室且耗时。甲真菌病检查是一种简单、快速且廉价的技术,可帮助临床医生提高甲真菌病的诊断准确性。本研究旨在确定甲真菌病的常见甲下镜下表现,并将其与甲真菌病的临床亚型相关联。

方法

本研究在印度北部一家三级保健医院的皮肤科门诊进行,持续 6 个月。通过氢氧化钾(KOH)载玻片对临床诊断为甲真菌病的病例进行确认。在获得书面知情同意后,这些患者接受 DermLite II 混合 m、3Gen、偏振模式、10×放大倍率的甲真菌病检查。记录常见的甲下镜下表现并对数据进行分析。

结果

本研究纳入了 60 例确诊的甲真菌病患者。观察到的常见甲下镜下表现为:65.5%的病例有甲剥离区锯齿状边缘和刺状突起、77.6%的病例有纵向条纹、82.7%的病例有远端不规则终止或“破坏模式”以及 62.1%的病例有甲变色。甲真菌病的临床类型与甲变色(p = 0.000)、锯齿状边缘和刺状突起(p = 0.015)以及远端不规则终止(p = 0.016)具有统计学显著相关性。

结论

甲真菌病检查可以作为临床诊断甲真菌病的辅助工具,以减轻对直接显微镜检查和培养的需求。

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