Ankad Balachandra S, Gupta Aakash, Alekhya Rallapalli, Saipriya Morlawar
Department of Dermatology, S.Nijalingappa Medical College, Bagalkot, Karnataka, India.
La Belle Skin Clinic, West Maredpally, Secunderbad, Telangana, India.
Indian Dermatol Online J. 2020 Sep 19;11(5):777-783. doi: 10.4103/idoj.IDOJ_475_19. eCollection 2020 Sep-Oct.
Clinical differentiation of onycholysis due to various etiologies is difficult task that compels to do invasive investigations to arrive at accurate diagnosis. Wrong diagnosis often leads to treatment failure and physicians and patient's anxiety. Dermoscopic patterns in nail psoriasis, onychomycosis are well established. Here, authors attempted to describe dermoscopic patterns in onycholysis due to psoriasis, onychomycosis and trauma in skin of color.
Study was conducted in a tertiary hospital in Southern India. Ethical clearance and informed consent from patients was obtained. Sixty consecutive patients who attended dermatology outpatient department with onycholysis were included in the study. Nail potassium hydroxide (KOH) study was done in all the cases. Onychoscopy was done with DermLite 3 with ultrasound gel as interface medium.
Totally 60 patients (42 males; 18 females) with onycholysis were included. Mean age was 37 years (range; 6-68 years). KOH was positive in 22 (36.6%) cases. Onychoscopy showed proximal erythematous rim, red dots, splinter hemorrhages in 23(65.71), 26 (74.28) and 21(60) in nail psoriasis respectively. Spiked and jagged-edges, aurora borealis and ruins pattern (65%) suggestive of onychomycosis were seen in 18(90%), 17 (85%) and 13 (65%) patients respectively. Plain edges without erythema or spikes were noted in 5 (8.33%) in traumatic onycholysis group.
Onychoscopy is a non- invasive modality to diagnose psoriasis, onychomycosis and traumatic involvement of nail apparatus by demonstrating characteristic patterns. Hence, it also plays an important role in effective management of such cases.
临床上鉴别各种病因导致的甲分离是一项艰巨的任务,往往需要进行侵入性检查才能得出准确诊断。错误的诊断常常导致治疗失败以及医生和患者的焦虑。银屑病甲、甲真菌病的皮肤镜表现已得到充分证实。在此,作者试图描述有色人种中银屑病、甲真菌病和外伤所致甲分离的皮肤镜表现。
研究在印度南部的一家三级医院进行。获得了患者的伦理批准和知情同意。连续60例因甲分离就诊于皮肤科门诊的患者被纳入研究。所有病例均进行了指甲氢氧化钾(KOH)检查。使用DermLite 3并以超声凝胶作为界面介质进行甲镜检查。
共纳入60例甲分离患者(42例男性;18例女性)。平均年龄为37岁(范围:6 - 68岁)。22例(36.6%)病例KOH检查呈阳性。甲镜检查显示,银屑病甲中分别有23例(65.71%)出现近端红斑边缘、26例(74.28%)出现红点、21例(60%)出现裂片形出血。甲真菌病组分别有18例(90%)、17例(85%)和13例(65%)患者出现提示甲真菌病的尖刺状和锯齿状边缘、北极光和废墟样表现(65%)。外伤性甲分离组有5例(8.33%)观察到边缘平整,无红斑或尖刺。
甲镜检查通过显示特征性表现,是诊断银屑病、甲真菌病以及甲装置外伤累及的一种非侵入性方法。因此,它在这类病例的有效管理中也起着重要作用。