Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS.
Department of Pathology, Dalhousie University, Halifax, NS.
J Obstet Gynaecol Can. 2021 Apr;43(4):497-499. doi: 10.1016/j.jogc.2020.12.006.
Septic shock after abortion is an important cause of global maternal mortality but is rarely encountered in developed countries. We describe a case of septic abortion with a novel associated pathogen: Neisseria meningitidis. A 30-year-old multiparous woman presented in septic shock after an incomplete spontaneous abortion. She received empiric antibiotics and vasopressors, underwent an urgent dilatation and curettage, and was admitted to the intensive care unit. Her blood cultures and endometrial tissue were positive for N. meningitidis. Antibiotics were adjusted based on culture, and the patient recovered. Septic shock requires prompt identification, antibiotic administration, and source control. Here, we identify an uncommon pathogen associated with septic abortion and highlight the importance of broad empiric and subsequent culture-guided antibiotic choice to ensure coverage.
流产后感染性休克是全球产妇死亡的一个重要原因，但在发达国家很少见。我们描述了一例感染性流产的病例，其相关病原体较新颖：脑膜炎奈瑟菌。
一位 30 岁的多产妇在不完全自然流产后继发感染性休克。她接受了经验性抗生素和血管加压药治疗，进行了紧急刮宫术，并入住重症监护病房。她的血液培养和子宫内膜组织均为脑膜炎奈瑟菌阳性。根据培养结果调整了抗生素，患者康复。感染性休克需要迅速识别、给予抗生素和控制源头。在这里，我们发现了一种与感染性流产相关的不常见病原体，并强调了广泛使用经验性抗生素治疗和随后进行培养指导的抗生素选择的重要性，以确保覆盖范围。
