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微孔聚氨酯移植物中自体和同源血小板行为的比较。绵羊的实验研究。

A comparison of the behaviour of autologous and homologous platelets in microporous polyurethane grafts. An experimental study in sheep.

作者信息

Dougan P, Lannerstad O, Bergqvist D

机构信息

Department of Experimental Research, University of Lund, General Hospital, Malmö, Sweden.

出版信息

Acta Chir Scand. 1988 Mar;154(3):185-90.

PMID:3376674
Abstract

In experimental studies in sheep the behaviour of autologous and homologous platelets in microporous polyurethane grafts was compared at a flow rate of 25 ml/min. The grafts were interposed to replace segments of resected carotid arteries. The deposition of 32P-labelled platelets on the graft wall was recorded, as were graft patency, thrombus weight and thrombus-free surface. Compared to autologous platelets, homologous platelets accumulated over longer periods of time and in greater numbers, leading to deposition of larger amounts of thrombus material and reduced patency.

摘要

在对绵羊的实验研究中,以25毫升/分钟的流速比较了微孔聚氨酯移植物中自体和同源血小板的行为。将移植物插入以替代切除的颈动脉段。记录了32P标记的血小板在移植物壁上的沉积情况,以及移植物通畅情况、血栓重量和无血栓表面。与自体血小板相比,同源血小板在更长时间内积累且数量更多,导致更多血栓物质沉积并降低了通畅性。

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