Jensen N, Lindblad B, Dougan P, Bergqvist D
Department of Surgery, Lund University, Malmö General Hospital, Sweden.
Vasa. 1992;21(4):365-8.
The early thrombogenicity of dacron vascular grafts with and without impregnation with collagen (n = 7) or gelatin (n = 7) was evaluated in a sheep carotid artery interposition model. Autologous platelets were labelled with 32P and reinjected. Flow was reduced to 25 ml/min to mimic a situation with poor run-off and the graft thrombogenicity was studied for 4 hours. The results showed no difference as regards patency, thrombus-free surface, or uptake of 32P-labelled platelets between collagen- or gelatin-impregnated grafts and their parent dacron grafts. Thus, no difference in early graft thrombogenicity could be documented.
在绵羊颈动脉搭桥模型中评估了有或没有用胶原蛋白（n = 7）或明胶（n = 7）浸渍的涤纶血管移植物的早期血栓形成性。用32P标记自体血小板并重新注入。将血流减少至25 ml/min以模拟血流不畅的情况，并研究移植物血栓形成性4小时。结果显示，胶原蛋白或明胶浸渍的移植物与其母体涤纶移植物在通畅性、无血栓表面或32P标记血小板的摄取方面没有差异。因此，无法证明早期移植物血栓形成性存在差异。
