大鼠脑内过氧化物酶体及邻苯二甲酸二（2-乙基己基）酯在出生后发育过程中的影响。一项电子显微镜研究。
Peroxisomes in the rat brain and the effects of di-(2-ethylhexyl) phthalate during postnatal development. An electron-microscopic study.
作者信息
Dabholkar A S
机构信息
Department of Biological Sciences, Wright State University, Dayton, Ohio.
出版信息
Acta Anat (Basel). 1988;131(3):218-21. doi: 10.1159/000146517.
PMID:3376726
Abstract
Peroxisomes were identified in the neurons of cerebral cortex of 12-day-old suckling rats from normal and plasticizer di-(2-ethylhexyl) phthalate (DEHP)-fed mothers. The study suggests that DEHP passed to the pups through the mother's milk during nursing can induce peroxisomal proliferation in neurons during postnatal development.
摘要
在来自正常饲养的母亲以及喂食增塑剂邻苯二甲酸二（2-乙基己基）酯（DEHP）的母亲的12日龄乳鼠的大脑皮层神经元中发现了过氧化物酶体。该研究表明，哺乳期通过母乳传递给幼崽的DEHP可在出生后发育过程中诱导神经元中的过氧化物酶体增殖。
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