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皮肤恶性黑色素瘤的不寻常形态学表现:一例罕见病例报告

Unusual Morphological Presentation of Cutaneous Malignant Melanoma: A Rare Case Report.

作者信息

Dash Gaurav, Pradhan Swetalina, Naik Subhasini

机构信息

Department of Dermatology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Dermatology, All India Institute of Medical Sciences, Patna, Bihar, India.

出版信息

Indian Dermatol Online J. 2021 Jan 16;12(1):139-141. doi: 10.4103/idoj.IDOJ_387_20. eCollection 2021 Jan-Feb.

DOI:10.4103/idoj.IDOJ_387_20
PMID:33768036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7982043/
Abstract

Cutaneous malignant melanoma is a rapidly progressing skin tumor accounting for most deaths from skin malignancies. Four morphological variants (nodular, superficial spreading, lentigo maligna, and acral lentiginous) are described in the literature. Here we are reporting malignant melanoma in a 35-year-old male who presented with depigmented plaques with few hyperpigmented areas and extensive overlying scaling. The patient progressed to the nodular stage within 2 weeks and succumbed to death during chemotherapy. We are reporting such rare presentation of malignant melanoma to create awareness among dermatologists to avoid misdiagnosis and delayed treatment which can lead to rapid progression and fatal outcome.

摘要

皮肤恶性黑色素瘤是一种进展迅速的皮肤肿瘤,是皮肤恶性肿瘤导致死亡的主要原因。文献中描述了四种形态学变异型(结节型、浅表扩散型、恶性雀斑样痣型和肢端雀斑样痣型)。在此,我们报告一例35岁男性的恶性黑色素瘤,该患者表现为色素脱失斑,伴有少量色素沉着区,其上有广泛的鳞屑。患者在2周内进展至结节期,并在化疗期间死亡。我们报告这种罕见的恶性黑色素瘤表现,以提高皮肤科医生的认识,避免误诊和延误治疗,因为这可能导致疾病快速进展和致命后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/eba7d356bfe5/IDOJ-12-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/9cf06c28f4e0/IDOJ-12-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/2fbf4c1cd4c6/IDOJ-12-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/eba7d356bfe5/IDOJ-12-139-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/9cf06c28f4e0/IDOJ-12-139-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/2fbf4c1cd4c6/IDOJ-12-139-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01e/7982043/eba7d356bfe5/IDOJ-12-139-g003.jpg

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