Perestrelo Ana Paula, Miranda Gonçalo, Gonçalves Maria Inês, Belino Carolina, Ballesteros Rosa
Centro Hospitalar Universitário Cova da Beira, Alameda Pêro da Covilhã, Covilhã, Portugal.
Eur J Case Rep Intern Med. 2021 Feb 17;8(3):002309. doi: 10.12890/2021_002309. eCollection 2021.
Copper, as a salt, is toxic and has the potential to harm multiple organs. Copper intoxication causes intravascular haemolysis followed by liver and kidney failure that can be fatal. We present a case of chronic copper sulfate poisoning in a 66-year-old man with dysphagia to solids and liquids, anaemia, acute kidney injury, liver cytolysis and hypocalcaemia. The patient improved with supportive care, but chronic kidney disease was established. Anamnesis was crucial for the diagnosis, given the non-specific signs and symptoms. The history of chronic exposure to pest treatment with a blue dust cloud made us suspect copper sulfate poisoning.
Copper sulfate poisoning is a relatively uncommon illness nowadays but can still be seen in clinical practice and should be kept in mind.It has non-specific signs and symptoms such as dysgeusia, abdominal pain, vomiting, muscle cramps or spasms, diarrhoea, ink-like urine, jaundice, anaemia and seizures.The diagnosis is based on clinical presentation and laboratory examinations upon a history of exposure to copper sulfate-containing products.
铜作为一种盐类是有毒的，有可能损害多个器官。铜中毒会导致血管内溶血，随后引发肝肾功能衰竭，可能会致命。我们报告一例66岁男性慢性硫酸铜中毒病例，该患者出现固体和液体吞咽困难、贫血、急性肾损伤、肝细胞溶解和低钙血症。患者经支持治疗后病情好转，但确诊为慢性肾病。鉴于症状和体征不具有特异性，既往史对诊断至关重要。长期接触蓝色粉尘状害虫防治剂的病史使我们怀疑为硫酸铜中毒。
硫酸铜中毒如今是一种相对罕见的疾病，但在临床实践中仍可见到，应予以关注。它具有非特异性的症状和体征，如味觉障碍、腹痛、呕吐、肌肉痉挛或抽搐、腹泻、酱油色尿、黄疸、贫血和癫痫发作。诊断基于接触含硫酸铜产品的病史、临床表现及实验室检查。
