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[急性硫酸铜中毒:一例病例报告的病理生理学与治疗]

[Acute cupric sulfate intoxication: pathophysiology and therapy about a case report].

作者信息

Faure A, Mathon L, Poupelin J C, Allaouchiche B, Chassard D

机构信息

Service d'anesthésie-réanimation, hôpital de l'Hôtel-Dieu, 1, place de l'Hôpital, 69288 Lyon cedex 02, France.

出版信息

Ann Fr Anesth Reanim. 2003 Jun;22(6):557-9. doi: 10.1016/s0750-7658(03)00132-1.

Abstract

A case of acute copper sulfate intoxication is presented here, as an illustration of high toxic copper dose. A 38-years-old patient with a light mental deficit ingested half a glass of copper sulfate. This patient first suffered from nausea and vomiting, then an intravascular haemolysis occurred during the hospitalisation in our intensive care unit. The outcome was favourable under aetiologic and symptomatic treatment: administration of D-penicillamine as a copper antidote and packed red cell transfusion. The patient left the intensive care unit after 9 days. Acute copper intoxication is not an exceptional situation, with a potentially severe outcome.

摘要

本文介绍了一例急性硫酸铜中毒病例,以说明高剂量铜的毒性。一名38岁有轻度智力缺陷的患者摄入了半杯硫酸铜。该患者最初出现恶心和呕吐,随后在我们重症监护病房住院期间发生了血管内溶血。在病因治疗和对症治疗下,结果良好:给予D-青霉胺作为铜解毒剂并输注浓缩红细胞。患者在9天后离开重症监护病房。急性铜中毒并非罕见情况,可能会导致严重后果。

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