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一名年轻女性的血管内溶血、高铁血红蛋白血症和急性肾衰竭

Intravascular Hemolysis, Methemogolbinemia and Acute Renal Failure in a Young Female.

作者信息

Gupta Ashish, Puri Saurabh, Aggarwal Neeru P, Randhwa Gulshan S, Jha Prem Mohan

机构信息

Senior Consultant, Max Super Specialty Hospital, Vaishali, Ghaziabad, Uttar Pradesh, India.

Medicine, Max Super Specialty Hospital, Vaishali, Ghaziabad, Uttar Pradesh, India.

出版信息

Indian J Nephrol. 2023 Mar-Apr;33(2):136-139. doi: 10.4103/ijn.ijn_410_21. Epub 2022 Aug 8.

Abstract

Copper sulfate occurs as large blue crystals in nature, commonly known as "blue vitriol" or "blue stone." It is a potentially lethal poison with significant mortality. Copper sulfate is a powerful oxidizing agent and causes corrosive injury to the mucous membrane. The clinical course involves intravascular hemolysis resulting in anemia, jaundice, and renal failure. Laboratory diagnosis of the condition is not an issue; the difficulty is suspecting it, promptly initiating chelation therapy, and other supportive symptomatic treatment. We present a case of copper sulfate poisoning in a young female with suicidal intent resulting in severe acute toxicity, which was successfully managed by copper chelator (d-Penicillamine) and other supportive measures.

摘要

硫酸铜在自然界中以大的蓝色晶体形式存在,通常被称为“蓝矾”或“胆矾”。它是一种具有显著致死率的潜在致命毒药。硫酸铜是一种强氧化剂,会对黏膜造成腐蚀性损伤。临床过程包括血管内溶血,导致贫血、黄疸和肾衰竭。该病症的实验室诊断不成问题;困难在于怀疑该病、及时启动螯合疗法以及其他支持性对症治疗。我们报告一例有自杀意图的年轻女性硫酸铜中毒病例,该病例导致严重急性毒性反应,通过铜螯合剂(青霉胺)和其他支持措施成功得到处理。

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