Matsuo Y, Kawashima K, Nakata S, Shimizu N, Imai K, Yamanaka H
Department of Urology, School of Medicine, Gunma University.
Hinyokika Kiyo. 1988 Feb;34(2):297-300.
Between 1961 and 1985, 44 cases of penile cancer were experienced at Gunma University Hospital. We statistically analyzed 42 of them. The average age was 56.9 years old, ranging from 28 to 86 years old. Interval from onset of the disease to first visit to our hospital ranged from 0 to 50 months, averaging 9 months. The main chief complaints were mass formation, spontaneous pain, ulceration, and abnormality of urinary stream. More than 75% of them had phimosis. Thirty-one percent had stage 1, 29% stage 2, 38% stage 3, and 2% stage 4 cancer, according to Jackson's classification. All of them were diagnosed with squamous cell carcinoma. Surgical treatment was given to 37 patients (radical or partial penectomy was performed in most cases). Chemotherapy was given to 23 patients (main chemotherapeutic agent was bleomycin or peplomycin) and irradiation to 26 patients. Five-year survival was seen in 77% of the cases, 92% in low stage group (stage 1 and 2) and 63% in high stage group (stage 3 and 4). Ten-year survival was seen in 62% of the cases, 79% in low stage group and 43% in high stage group (Kaplan-Meier method).
1961年至1985年间，群马大学医院共收治44例阴茎癌患者。我们对其中42例进行了统计学分析。患者平均年龄为56.9岁，年龄范围在28岁至86岁之间。从发病到首次来我院就诊的时间间隔为0至50个月，平均为9个月。主要主诉为肿物形成、自发疼痛、溃疡和尿流异常。超过75%的患者存在包茎。根据杰克逊分类法，31%为1期癌，29%为2期癌，38%为3期癌，2%为4期癌。所有患者均被诊断为鳞状细胞癌。37例患者接受了手术治疗（大多数病例行根治性或部分阴茎切除术）。23例患者接受了化疗（主要化疗药物为博来霉素或培普利霉素），26例患者接受了放疗。77%的病例存活5年，低分期组（1期和2期）为92%，高分期组（3期和4期）为63%。62%的病例存活10年，低分期组为79%，高分期组为43%（Kaplan-Meier法）。
