Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Research Institute Children's Cancer Center Hamburg, Hamburg, Germany.
Neuropathol Appl Neurobiol. 2021 Oct;47(6):889-890. doi: 10.1111/nan.12713. Epub 2021 Apr 5.
HOXB13 is expressed in the tail bud of the developing embryo as well as in cauda equina paragangliomas and in myxopapillary ependymomas. In contrast, pheochromocytomas and paraganglioma in other locations as well as many other tumors occuring in spinal cord regions are negative.
HOXB13 在发育胚胎的尾芽中以及尾侧脊副神经节瘤和黏液性乳头状室管膜瘤中表达。相比之下，其他部位的嗜铬细胞瘤和副神经节瘤以及脊髓区域发生的许多其他肿瘤均为阴性。
