Bruch J S, Stein R S, Oates J A
Department of Medicine, Vanderbilt University School of Medicine, Nashville.
Am J Med Sci. 1988 May;295(5):466-8. doi: 10.1097/00000441-198805000-00009.
Essential thrombocythemia (ET) is a myeloproliferative disorder characterized by marked thrombocytosis with associated hemorrhagic, thrombotic and embolic complications caused by platelet dysfunction. In this report we describe two cases of ET and moderate to severe hypertension associated with renal artery stenosis and renal microvascular lesions. In both cases treatment of the hematologic disorder resulted in reduction of blood pressure and improvement of clinical symptoms.
原发性血小板增多症(ET)是一种骨髓增殖性疾病,其特征为显著的血小板增多,并伴有因血小板功能障碍引起的出血、血栓形成和栓塞并发症。在本报告中,我们描述了两例原发性血小板增多症合并中重度高血压的病例,这两例患者均伴有肾动脉狭窄和肾微血管病变。在这两例病例中,对血液系统疾病的治疗均导致血压降低和临床症状改善。