食用辣椒和甜椒与老年人肌肉减少症风险降低有关。
Consumption of chilies and sweet peppers is associated with lower risk of sarcopenia in older adults.
机构信息
Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
College of Pharmacy, Tianjin Medical University, Tianjin, China.
出版信息
Aging (Albany NY). 2021 Mar 26;13(6):9135-9142. doi: 10.18632/aging.104168.
BACKGROUND
Sarcopenia is an aging-related loss of muscle mass and function, which induces numerous adverse outcomes. Capsaicin and capsiate, separately extracted from chilies and sweet peppers, have the potential to induce muscle hypertrophy via activation of transient receptor potential vanilloid 1. The present study aimed to investigate whether chili and sweet pepper consumption are related to sarcopenia in the elderly general population.
METHODS
A cross-sectional study with 2,451 participants was performed. Dietary chili and sweet pepper consumption were assessed using a validated self-administered food frequency questionnaire. Sarcopenia was defined according to the consensus of the Asian Working Group for Sarcopenia. Logistic regressions were performed to measure the effect of chili and sweet pepper consumption on sarcopenia.
RESULTS
The prevalence of sarcopenia was 16.1%. After adjustment for potential confounding variables, the odds ratios (95% confidence intervals) for sarcopenia across chili and sweet pepper consumption categories were 1.00 (reference) for almost never, 0.73 (0.55, 0.97) and 0.73 (0.56, 0.96) for ≤1 time/week, 0.60 (0.39, 0.90) and 0.66 (0.45, 0.95) for ≥2-3 times/week (both for trend <0.01), respectively.
CONCLUSION
The present study showed that higher consumption of chilies and sweet peppers was related to a lower risk of sarcopenia in older adults.
背景
肌少症是一种与衰老相关的肌肉质量和功能丧失，会导致许多不良后果。辣椒素和辣椒素分别从辣椒和甜椒中提取，通过激活瞬时受体电位香草酸 1 有可能诱导肌肉肥大。本研究旨在探讨老年人一般人群中食用辣椒和甜椒是否与肌少症有关。
方法
进行了一项横断面研究，共纳入 2451 名参与者。使用经过验证的自我管理食物频率问卷评估膳食中辣椒和甜椒的摄入量。根据亚洲肌少症工作组的共识，定义肌少症。使用逻辑回归来衡量辣椒和甜椒摄入对肌少症的影响。
结果
肌少症的患病率为 16.1%。在调整潜在混杂变量后，辣椒和甜椒摄入量类别中肌少症的比值比（95%置信区间）分别为几乎从不（0.73，0.55，0.97）和每周 1-3 次（0.60，0.39，0.90）和每周≥2-3 次（0.66，0.45，0.95）（均为趋势检验<0.01）。
结论
本研究表明，较高的辣椒和甜椒摄入量与老年人肌少症风险降低相关。
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