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膳食模式与老年人肌少症:天津慢性低度系统性炎症与健康(TCLSIH)研究。

Dietary patterns and sarcopenia in elderly adults: the Tianjin Chronic Low-grade Systemic Inflammation and Health (TCLSIH) study.

机构信息

Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, People's Republic of China.

Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, People's Republic of China.

出版信息

Br J Nutr. 2022 Sep 14;128(5):900-908. doi: 10.1017/S0007114521003871. Epub 2021 Sep 27.

DOI:10.1017/S0007114521003871
PMID:34565491
Abstract

Sarcopenia is a core contributor to several health consequences, including falls, fractures, physical limitations and disability. The pathophysiological processes of sarcopenia may be counteracted with the proper diet, delaying sarcopenia onset. Dietary pattern analysis is a whole diet approach used to investigate the relationship between diet and sarcopenia. Here, we aimed to investigate this relationship in an elderly Chinese population. A cross-sectional study with 2423 participants aged more than 60 years was performed. Sarcopenia was defined based on the guidelines of the Asian Working Group for Sarcopenia, composed of low muscle mass plus low grip strength and/or low gait speed. Dietary data were collected using a FFQ that included questions on 100 food items along with their specified serving sizes. Three dietary patterns were derived by factor analysis: sweet pattern, vegetable pattern and animal food pattern. The prevalence of sarcopenia was 16·1 %. The higher vegetable pattern score and animal food pattern score were related to lower prevalence of sarcopenia ( = 0·006 and < 0·001, respectively); the multivariate-adjusted OR of the prevalence of sarcopenia in the highest . lowest quartiles were 0·54 (95 % CI 0·34, 0·86) and 0·50 (95 % CI 0·33, 0·74), separately. The sweet pattern score was not significantly related to the prevalence of sarcopenia. The present study showed that vegetable pattern and animal food pattern were related to a lower prevalence of sarcopenia in Chinese older adults. Further studies are required to clarify these findings.

摘要

肌少症是多种健康后果的核心促成因素,包括跌倒、骨折、身体活动受限和残疾。肌少症的病理生理过程可以通过适当的饮食来对抗,从而延缓肌少症的发生。饮食模式分析是一种整体饮食方法,用于研究饮食与肌少症之间的关系。在这里,我们旨在调查中国老年人群体中的这种关系。进行了一项横断面研究,纳入了 2423 名年龄在 60 岁以上的参与者。肌少症根据亚洲肌少症工作组的指南定义,包括低肌肉量加低握力和/或低步态速度。使用包含 100 种食物及其特定份量的问卷的 FFQ 收集饮食数据。通过因子分析得出了三种饮食模式:甜食模式、蔬菜模式和动物食品模式。肌少症的患病率为 16.1%。较高的蔬菜模式评分和动物食品模式评分与较低的肌少症患病率相关(=0.006 和 <0.001);最高和最低四分位数的肌少症患病率的多变量调整 OR 分别为 0.54(95%CI 0.34,0.86)和 0.50(95%CI 0.33,0.74)。甜食模式评分与肌少症的患病率无显著相关性。本研究表明,蔬菜模式和动物食品模式与中国老年人较低的肌少症患病率有关。需要进一步的研究来阐明这些发现。

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Nutrients. 2024 May 30;16(11):1707. doi: 10.3390/nu16111707.
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Nutrients. 2021 Nov 29;13(12):4310. doi: 10.3390/nu13124310.