基于 GATE 的发射断层成像系统的高级蒙特卡罗模拟。
Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.
机构信息
Université de Lyon, CREATIS, CNRS UMR5220, Inserm U1294, INSA-Lyon, Université Lyon 1, Lyon, France.
Jagiellonian University, Kraków, Poland.
出版信息
Phys Med Biol. 2021 May 14;66(10). doi: 10.1088/1361-6560/abf276.
Abstract
Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand and create innovative emission tomography systems. In this paper, we reviewed the recent developments that have been proposed to simulate modern detectors and provide a comprehensive report on imaging systems that have been simulated and evaluated in GATE. Additionally, some methodological developments that are not specific for imaging but that can improve detector modeling and provide computation time gains, such as Variance Reduction Techniques and Artificial Intelligence integration, are described and discussed.
摘要
基于 Geant4 工具包构建，GATE 经过 15 年以上的协作开发，用于设计基于核的成像系统的蒙特卡罗模拟。特别是，研究人员和工业界使用它来设计、优化、理解和创建创新的发射断层成像系统。在本文中，我们回顾了最近提出的用于模拟现代探测器的发展，并提供了在 GATE 中模拟和评估的成像系统的综合报告。此外，还描述和讨论了一些不是专门用于成像但可以改进探测器建模并提供计算时间收益的方法开发，例如方差减少技术和人工智能集成。
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