Prasad Ashish, Prasad Manoj
National Institute of Plant Genourrent overview ome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India.
National Institute of Plant Genourrent overview ome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Virus Res. 2021 Jun;298:198402. doi: 10.1016/j.virusres.2021.198402. Epub 2021 Mar 23.
Viruses are obligate pathogens that cause a wide range of diseases across all kingdoms of life. They have a colossal impact on the economy and healthcare infrastructure world-wide. Plants and animals have developed sophisticated molecular mechanisms to defend themselves against viruses and viruses in turn hijack host mechanisms to ensure their survival inside their hosts. Long non-coding (lnc) RNAs have emerged as important macromolecules that regulate plant-virus and animal-virus interactions. Both pro-viral and anti-viral lncRNAs have been reported and they show immense potential to be used as markers and in therapeutics. The current review is focussed on the recent developments that have been made in viral interactions of animals and plants.
病毒是专性病原体，可在所有生物界中引发广泛的疾病。它们对全球经济和医疗基础设施产生了巨大影响。植物和动物已经进化出复杂的分子机制来抵御病毒，而病毒反过来又会劫持宿主机制以确保其在宿主体内的存活。长链非编码（lnc）RNA已成为调节植物-病毒和动物-病毒相互作用的重要大分子。已经报道了促病毒和抗病毒lncRNA，它们在用作标志物和治疗方面显示出巨大潜力。本综述重点关注动植物病毒相互作用方面的最新进展。
