Gago-Zachert Selma
Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany.
Virus Res. 2016 Jan 2;212:12-24. doi: 10.1016/j.virusres.2015.08.018. Epub 2015 Aug 28.
Transcriptome deep-sequencing studies performed during the last years confirmed that the vast majority of the RNAs transcribed in higher organisms correspond to several types of non-coding RNAs including long non-coding RNAs (lncRNAs). The study of lncRNAs and the identification of their functions, is still an emerging field in plants but the characterization of some of them indicate that they play an important role in crucial regulatory processes like flowering regulation, and responses to abiotic stress and plant hormones. A second group of lncRNAs present in plants is formed by viroids, exogenous infectious subviral plant pathogens well known since many years. Viroids are composed of circular RNA genomes without protein-coding capacity and subvert enzymatic activities of their hosts to complete its own biological cycle. Different aspects of viroid biology and viroid-host interactions have been elucidated in the last years and some of them are the main topic of this review together with the analysis of the state-of-the-art about the growing field of endogenous lncRNAs in plants.
过去几年进行的转录组深度测序研究证实，高等生物中转录的绝大多数RNA对应于几种类型的非编码RNA，包括长链非编码RNA（lncRNA）。lncRNA的研究及其功能鉴定在植物领域仍是一个新兴领域，但对其中一些lncRNA的表征表明，它们在诸如开花调控、对非生物胁迫和植物激素的反应等关键调控过程中发挥着重要作用。植物中存在的第二类lncRNA由类病毒组成，类病毒是多年来广为人知的外源感染性亚病毒植物病原体。类病毒由没有蛋白质编码能力的环状RNA基因组组成，并破坏其宿主的酶活性以完成自身的生物循环。过去几年已经阐明了类病毒生物学和类病毒与宿主相互作用的不同方面，其中一些是本综述的主要主题，同时还分析了植物中内源性lncRNA这一不断发展的领域的最新状况。
