Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Evid Based Dent. 2021 Jan;22(1):44-45. doi: 10.1038/s41432-021-0159-1.
Data sources PubMed, Scopus, Web of Science, MEDLINE and CINAHL.Study selection Randomised controlled trials, cross-sectional studies and cohort studies.Data extraction and synthesis Two reviewers independently extracted data using piloted forms and contacted authors if relevant data were missing. Assessment of quality was done using the Newcastle-Ottawa scale (NOS) for both cohort and cross-sectional studies. The score of NOS ranged from 1-9, where 6-7 is considered moderate quality while 8-9 is high quality.Results Seventeen studies were included in the review (13 cross-sectional and four cohort). Seven out of 13 cross-sectional studies scored ≤5 which indicates poor quality. The four case-control studies were of moderate quality. Overall, there is limited evidence that patients with multiple sclerosis (MS) have more dental caries or gingival disease. However, evidence suggests that patients with MS have more risk of periodontal disease and poor oral hygiene. The evidence also suggests a moderate association between MS and temporomandibular disorders (TMD).Conclusions With the exception of TMD, current evidence does not establish an association between MS and most oral health conditions. More high-quality evidence is needed to further explore and establish an association.
PubMed、Scopus、Web of Science、MEDLINE 和 CINAHL。
随机对照试验、横断面研究和队列研究。
两位审稿人使用预编程表格独立提取数据，如果相关数据缺失，他们会联系作者。使用纽卡斯尔-渥太华量表（NOS）对队列和横断面研究进行质量评估。NOS 的评分范围为 1-9，其中 6-7 为中等质量，8-9 为高质量。
共纳入 17 项研究（13 项横断面研究和 4 项队列研究）。13 项横断面研究中有 7 项评分≤5，表明质量较差。4 项病例对照研究为中等质量。总体而言，有有限的证据表明多发性硬化症（MS）患者的龋齿或牙龈疾病更多。然而，有证据表明 MS 患者牙周病和口腔卫生不良的风险更高。证据还表明 MS 与颞下颌关节紊乱（TMD）之间存在中度关联。
除 TMD 外，目前的证据并未确定 MS 与大多数口腔健康状况之间存在关联。需要更多高质量的证据来进一步探索和建立关联。
