Chatzopoulos Georgios S, Jiang Ziou, Marka Nicholas, Wolff Larry F
Division of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA.
Department of Preventive Dentistry, Periodontology and Implant Biology, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
J Pers Med. 2023 May 11;13(5):814. doi: 10.3390/jpm13050814.
The aim of this study was to analyze the relationship between extent, severity (stage), and rate of progression (grade) of periodontitis with systemic diseases as well as smoking using a large database.
Patients' records identified in the BigMouth Dental Data Repository with a periodontal diagnosis based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions were evaluated. Patients were further categorized based on extent, severity, and rate of progression. Data were extracted from patients' electronic health records including demographic characteristics, dental procedural codes, and self-reported medical conditions, as well as the number of missing teeth.
A total of 2069 complete records were ultimately included in the analysis. Males were more likely to have generalized periodontitis and stage III or IV periodontitis. Older individuals were more likely diagnosed with grade B and stage III or IV periodontitis. Individuals with generalized disease, grade C, and stage IV demonstrated a significantly higher number of missing teeth. Higher numbers of tooth loss reported during supportive periodontal treatment were noted in generalized disease and stage IV periodontitis. Multiple sclerosis and smoking were significantly associated with grade C periodontitis.
Within the limitations of this retrospective study that utilized the BigMouth dental data repository, smokers were significantly associated with rapid progression of periodontitis (grade C). Gender, age, number of missing teeth, and number of tooth loss during supportive periodontal treatment were associated with disease characteristics.
本研究旨在利用一个大型数据库分析牙周炎的范围、严重程度（分期）和进展速率（分级）与全身性疾病以及吸烟之间的关系。
对在大嘴牙科数据储存库中根据2017年牙周和种植体周围疾病及状况分类研讨会确诊为牙周炎的患者记录进行评估。根据范围、严重程度和进展速率对患者进一步分类。从患者的电子健康记录中提取数据，包括人口统计学特征、牙科程序代码、自我报告的医疗状况以及缺失牙数量。
最终共有2069份完整记录纳入分析。男性更易患广泛性牙周炎以及III期或IV期牙周炎。年龄较大者更易被诊断为B级以及III期或IV期牙周炎。患有广泛性疾病、C级和IV期的个体缺失牙数量显著更多。在支持性牙周治疗期间报告的牙齿脱落数量较多的情况见于广泛性疾病和IV期牙周炎。多发性硬化症和吸烟与C级牙周炎显著相关。
在这项利用大嘴牙科数据储存库的回顾性研究的局限性范围内，吸烟者与牙周炎的快速进展（C级）显著相关。性别、年龄、缺失牙数量以及支持性牙周治疗期间的牙齿脱落数量与疾病特征相关。
