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Sensitivity and reliability of DNA-based mutation analysis by allele-specific digital PCR to follow resistant BCR-ABL1-positive cells.

作者信息

Polivkova Vaclava, Benesova Adela, Zizkova Hana, Koblihova Jitka, Curik Nikola, Motlova Eliska, Klamova Hana, Salek Cyril, Machova Polakova Katerina

机构信息

Institute of Hematology and Blood Transfusion, Prague, Czech Republic.

Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.

出版信息

Leukemia. 2021 Aug;35(8):2419-2423. doi: 10.1038/s41375-021-01226-0. Epub 2021 Mar 26.

DOI:10.1038/s41375-021-01226-0
PMID:33772144
Abstract
摘要

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T315I mutation in Ph-positive acute lymphoblastic leukemia is associated with a highly aggressive disease phenotype: three case reports.Ph 阳性急性淋巴细胞白血病中的 T315I 突变与高度侵袭性疾病表型相关：三例病例报告。
Anticancer Res. 2012 May;32(5):1779-83.
血液系统和实体瘤中的可测量残留病灶（MRD）检测
Leukemia. 2024 Jun;38(6):1202-1212. doi: 10.1038/s41375-024-02252-4. Epub 2024 Apr 18.
4
Resistance mutations in CML and how we approach them.CML 中的耐药突变及其应对策略。
Hematology Am Soc Hematol Educ Program. 2023 Dec 8;2023(1):469-475. doi: 10.1182/hematology.2023000447.
5
European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia.欧洲白血病网络实验室关于慢性髓性白血病诊断和管理的建议。
Leukemia. 2023 Nov;37(11):2150-2167. doi: 10.1038/s41375-023-02048-y. Epub 2023 Oct 4.
6
Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.通过对基因组 DNA 的超高深度测序检测 BCR::ABL1 白血病中的激酶结构域突变。
Sci Rep. 2022 Jul 29;12(1):13057. doi: 10.1038/s41598-022-17271-3.
7
Wet-Etched Microchamber Array Digital PCR Chip for SARS-CoV-2 Virus and Ultra-Early Stage Lung Cancer Quantitative Detection.用于SARS-CoV-2病毒和超早期肺癌定量检测的湿法蚀刻微腔阵列数字PCR芯片
ACS Omega. 2022 Jan 7;7(2):1819-1826. doi: 10.1021/acsomega.1c05082. eCollection 2022 Jan 18.