Division of General Radiological Diagnostics, Department of Radiology, Medical University of Graz, Austria.
Rofo. 2021 Oct;193(10):1171-1182. doi: 10.1055/a-1401-0215. Epub 2021 Mar 26.
In the diagnosis of bone and soft-tissue sarcomas, the continuous advancement of various imaging modalities has improved the detection of small lesions, surgical planning, assessment of chemotherapeutic effects, and, importantly, guidance for surgery or biopsy.
This review was composed based on a PubMed literature search for the terms "bone sarcoma," "bone cancer" and "soft tissue sarcoma," "imaging," "magnetic resonance imaging", "computed tomography", "ultrasound", "radiography", and "radiomics" covering the publication period 2005-2020.
As discussed in this review, radiography, ultrasound, CT, and MRI all play key roles in the imaging evaluation of bone and soft-tissue sarcomas. In daily practice, advanced MRI techniques complement standard MRI but remain underused, as they are considered time-consuming, technically challenging, and not reliable enough to replace biopsy and histology. PET/MRI and radiomics have shown promise regarding the imaging of sarcomas in the future.
· Radiographs remain crucial in diagnostic imaging algorithms for sarcomas.. · US is an initial imaging study for the evaluation of superficial soft-tissue tumors.. · The role of CT continues to evolve as new techniques emerge.. · MRI allows the noninvasive evaluation of soft-tissue, osseous, and articular structures.. · Machine learning methods could improve personalized selection of therapy for patients with sarcoma..
· Igrec J, Fuchsjäger MH. Imaging of Bone and Soft-Tissue Sarcomas. Fortschr Röntgenstr 2021; 193: 1171 - 1182.
在骨与软组织肉瘤的诊断中，各种影像学手段的不断进步提高了对小病灶的检出率，有助于手术规划、化疗效果评估，重要的是，还为手术或活检提供了指导。
本综述基于对 2005 年至 2020 年期间的“骨肉瘤”、“骨癌”和“软组织肉瘤”、“成像”、“磁共振成像”、“计算机断层扫描”、“超声”、“射线照相术”和“放射组学”等术语的 PubMed 文献检索，进行文献综述。
正如本文所讨论的，射线照相术、超声、CT 和 MRI 在骨与软组织肉瘤的影像学评估中都发挥着关键作用。在日常实践中，高级 MRI 技术虽然补充了标准 MRI，但仍未得到充分应用，因为其被认为耗时、技术要求高，且不够可靠，无法替代活检和组织学。PET/MRI 和放射组学在未来的肉瘤成像方面显示出了一定的应用前景。
射线照相术在肉瘤的诊断成像算法中仍然至关重要。
US 是评估浅表软组织肿瘤的初始影像学研究。
随着新技术的出现，CT 的作用在不断发展。
MRI 可无创评估软组织、骨骼和关节结构。
机器学习方法可以提高肉瘤患者的个体化治疗选择。
Igrec J, Fuchsjäger MH. Imaging of Bone and Soft-Tissue Sarcomas. Fortschr Röntgenstr 2021; 193: 1171 - 1182.
