Department of Molecular and Biomedical Sciences, NC State University College of Veterinary Medicine, 1060 William Moore Drive, Raleigh, NC 27606, USA.
Vet Clin North Am Small Anim Pract. 2021 May;51(3):729-744. doi: 10.1016/j.cvsm.2021.01.012.
Cachexia and frailty can be described as independent entities yet are interrelated as constituents of malnutrition and the aging process. The unifying aspect is lean muscle loss, ultimately driven by inflammation and the adverse ramifications to pets with chronic, debilitating, or terminal disease states, including cancer. Modification to intake of dietary protein, fat, omega-3 fatty acids, and selected vitamins has shown benefit in management protocols as preventative and palliative care, but further investigation is imperative.
恶病质和衰弱可以被描述为独立的实体,但它们作为营养不良和衰老过程的组成部分相互关联。肌肉减少是两者的统一特征,最终由炎症和患有慢性、衰弱或终末期疾病状态的宠物(包括癌症)的不利后果驱动。改变饮食中蛋白质、脂肪、ω-3 脂肪酸和某些维生素的摄入已显示在管理方案中作为预防和姑息治疗有益,但进一步的研究是必要的。