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床旁超声(POCUS)在 COVID-19 住院患者中诊断近端深静脉血栓形成的应用,这些患者具有较高的低分子肝素预防率。

Point of care ultrasound (POCUS) in diagnosis of proximal deep vein thrombosis among COVID-19 hospitalized patients with a high rate of low molecular weight heparin prophylaxis.

机构信息

Internal Medicine Department, Hospital Universitario Clínico San Cecilio, Spain.

Infectious Diseases Department, Hospital Universitario Clínico San Cecilio, Spain.

出版信息

Med Clin (Barc). 2021 Aug 27;157(4):172-175. doi: 10.1016/j.medcli.2021.01.012. Epub 2021 Feb 27.

Abstract

BACKGROUND

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are both complications linked with COVID-19. Lower limb point-of-care clinical ultrasound (POCUS) could detect occult clots, helping decide whom to treat with anticoagulation.

OBJECTIVES

To determine proximal DVT prevalence with POCUS screening among hospitalized COVID-19 patients.

PATIENTS/METHODS: Lower limb POCUS was performed in all patients admitted either to the ward or intensive care unit (ICU) between April 22nd and 30th 2020. Clinical and laboratory features, prescriptions, thrombotic complications and outcomes were assessed.

RESULTS

87 patients were screened, of which 26 (29.8%) either had been discharged from ICU (19.5%) or were still in critical condition (10.3%). DVT was found in 4 patients (3 femoral, 1 popliteal), of which 1 had not received low molecular weight heparin (LMWH) prophylaxis. 21 CT pulmonary angiograms were performed, being positive for PE in 5 cases (23.8%); only 2 of these patients suffered DVT.

CONCLUSIONS

Screening lower extremities with POCUS did not find a high rate of DVT among patients receiving LMWH-prophylaxis. However, there was a noteworthy amount of PE without DVT.

摘要

背景

深静脉血栓形成(DVT)和肺栓塞(PE)都是与 COVID-19 相关的并发症。下肢即时护理临床超声(POCUS)可检测隐匿性血栓,有助于决定对哪些患者进行抗凝治疗。

目的

确定 COVID-19 住院患者中使用 POCUS 筛查的近端 DVT 患病率。

患者/方法:2020 年 4 月 22 日至 30 日期间,对所有入住病房或重症监护病房(ICU)的患者进行下肢 POCUS 检查。评估临床和实验室特征、处方、血栓并发症和结局。

结果

共筛查了 87 例患者,其中 26 例(29.8%)已从 ICU 出院(19.5%)或仍处于危急状态(10.3%)。4 例患者(3 例股静脉,1 例腘静脉)发现 DVT,其中 1 例未接受低分子肝素(LMWH)预防治疗。对 21 例 CT 肺动脉造影进行了检查,5 例(23.8%)呈阳性,其中 2 例患者患有 DVT。

结论

对接受 LMWH 预防治疗的患者进行下肢 POCUS 筛查并未发现 DVT 发生率较高。然而,存在大量无 DVT 的 PE。

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