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巴西一家转诊中心的新冠患者中深静脉血栓形成和死亡率增加。

Increased prevalence of deep vein thrombosis and mortality in patients with Covid-19 at a referral center in Brazil.

机构信息

Cardiology and Cardiovascular Surgery in Medicine School of Sao Jose do Rio Preto-FAMERP and CNPq (National Council for Research and Development), Brazil.

Vascular Surgery of Service Ecography in Hospital de Base-Medicine School of Sao Jose do Rio Preto-FAMERP-Brazil.

出版信息

Phlebology. 2022 Feb;37(1):21-25. doi: 10.1177/02683555211041931. Epub 2021 Sep 8.

DOI:10.1177/02683555211041931
PMID:34494482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8829736/
Abstract

BACKGROUND

Among the multiple complex pathophysiological mechanisms underlying Covid-19 pneumonia, immunothrombosis has been shown to play a key role.

OBJECTIVE

The aim of the present study was to assess the monthly prevalence of deep venous thrombosis in a university hospital that admitted 5159 patients with Covid-19 in the medical ward and intensive care unit (ICU) and investigate whether there has been an increase in the prevalence of deep vein thrombosis and dead recently.

METHOD

A clinical trial was conducted evaluating 5159 patients admitted to the university hospital, Hospital de Base in São Jose do Rio Preto-Brazil, with a positive test for Covid-19, the prevalence of monthly deep venous thrombosis and the increase in thrombotic and events and mortality in March 2020 to April 2021 compared to the previous January and February with March-April of 2021. The evaluated by Fisher's exact test.

RESULTS

The prevalence of deep vein thrombosis varied between the months of 0.26% to 7%, with an average of 2.5%. The months of March and April 2021 had a significant increase in venous thrombosis and mortality in relation to the months of January and February 2021.

CONCLUSION

The prevalence of deep venous thrombosis was variable during the months evaluated, since the beginning of Covid-19, but there was a significant increase in these last two months.

摘要

背景

在导致新冠肺炎肺炎的多种复杂病理生理机制中,免疫血栓形成被证明起着关键作用。

目的

本研究旨在评估一家大学附属医院收治的 5159 例新冠肺炎患者(在医疗病房和重症监护病房)中深静脉血栓形成的每月患病率,并调查深静脉血栓形成和最近死亡的患病率是否增加。

方法

进行了一项临床试验,评估了 5159 例入住巴西圣若泽-杜里奥普雷托市基础医院的新冠肺炎患者,这些患者的新冠病毒检测呈阳性,评估了每月深静脉血栓形成的患病率,并比较了 2020 年 3 月至 2021 年 4 月与 2021 年 1 月至 2 月相比,2020 年 3 月至 4 月深静脉血栓形成和事件以及死亡率的增加情况。采用 Fisher 精确检验进行评估。

结果

深静脉血栓形成的患病率在 0.26%至 7%之间变化,平均为 2.5%。2021 年 3 月和 4 月与 2021 年 1 月和 2 月相比,静脉血栓形成和死亡率显著增加。

结论

自新冠肺炎疫情开始以来,深静脉血栓形成的患病率在评估的几个月内有所不同,但在最近两个月显著增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f8/8829736/48f131b91b68/10.1177_02683555211041931-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f8/8829736/dd01dac77c95/10.1177_02683555211041931-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f8/8829736/48f131b91b68/10.1177_02683555211041931-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f8/8829736/dd01dac77c95/10.1177_02683555211041931-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7f8/8829736/48f131b91b68/10.1177_02683555211041931-fig2.jpg

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