Inagaki M, Sakakura Y, Shimizu T, Majima Y, Ukai K
Department of Otorhinolarygology, Mie University School of Medicine, Tsu, Japan.
Ann Otol Rhinol Laryngol. 1988 May-Jun;97(3 Pt 1):313-7. doi: 10.1177/000348948809700321.
We used transmission electron microscopy to study the mucous blanket of the promontory from children with otitis media with effusion. The vast majority of the epithelial cells were secretory, and the rest were ciliated. The mucous blanket consisted of the electron-lucent periciliary fluid and the mucous layer. In the mucous layer, two layers were identified: an inner layer with migrating cells, and an outer layer with specks. Moreover, there was a lucent zone over the nonciliated surface that was as high as the microvilli. The thickness of the periciliary layer was predominantly as great as that of the ciliary tips, which just make contact with the mucous layer; however, the mucous layer occasionally penetrated into the periciliary space. These findings indicated that there is a mucociliary dysfunction in the middle ear caused by a decrease in the number of ciliated cells, and an abnormal interaction between cilia and mucus that would interfere with ciliary movement. Thus, such a system would fail to transport the mucous blanket.
我们使用透射电子显微镜研究了分泌性中耳炎患儿岬部的黏液毯。绝大多数上皮细胞为分泌细胞，其余为纤毛细胞。黏液毯由电子透明的纤毛周液和黏液层组成。在黏液层中，可识别出两层：内层有迁移细胞，外层有斑点。此外，在无纤毛表面上方有一个与微绒毛一样高的透明区。纤毛周层的厚度主要与刚接触黏液层的纤毛尖端的厚度相同；然而，黏液层偶尔会侵入纤毛周间隙。这些发现表明，中耳存在黏液纤毛功能障碍，其原因是纤毛细胞数量减少，以及纤毛与黏液之间的异常相互作用会干扰纤毛运动。因此，这样的系统将无法输送黏液毯。
