Newberg L B, Ling V, Shamsuddin A M
Laryngoscope. 1985 Aug;95(8):921-3. doi: 10.1288/00005537-198508000-00007.
The pathologic changes of the middle ear and mastoid bone mucosa in two pediatric patients with long standing chronic serous otitis media were studied by electron and light microscopy. The embryological development of the eustachian tube, middle ear cleft, and mastoid bone suggests a common physiological and anatomical continuity. The histological changes by light and electron microscopy in these patients demonstrates the metaplastic changes of the basal cell of the mucosa differentiating into mucous and keratin cells. These metaplastic changes are associated with the exudative process known as chronic serous otitis media.
通过电子显微镜和光学显微镜研究了两名长期患有慢性浆液性中耳炎的儿科患者中耳和乳突骨黏膜的病理变化。咽鼓管、中耳裂和乳突骨的胚胎发育表明它们在生理和解剖学上具有共同的连续性。这些患者通过光学显微镜和电子显微镜观察到的组织学变化显示，黏膜基底细胞化生为黏液细胞和角质形成细胞。这些化生变化与被称为慢性浆液性中耳炎的渗出过程有关。
