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使用休克指数和乳酸来预测急诊科急性心力衰竭患者的死亡率。

Use of Shock Index and Lactate to Predict Mortality in Acute Heart Failure Patients in Emergency Department.

作者信息

Cetinkaya Hasan Basri, Gunes Harun

机构信息

Department of Emergency Medicine, Balikesir University School of Medicine, Balikesir, Turkey.

出版信息

J Coll Physicians Surg Pak. 2021 Mar;31(3):262-266. doi: 10.29271/jcpsp.2021.03.262.

Abstract

OBJECTIVE

To compare the usefulness of shock index (SI) and lactate for prediction of 24-hour and 28-day mortality in acute heart failure (AHF) patients.

STUDY DESIGN

A descriptive study. Place and Duration of the Study: Balikesir University Hospital, Balikesir, Turkey; from February 2019 to August 2020.

METHODOLOGY

One hundred and twelve AHF patients presenting to ED were recruited into the study. Usefulness of lactate and SI in predicting mortality at 24-hour and 28-day, was evaluated.

RESULTS

The area under the curve (AUC) was found to be 0.825 for lactate and 0.818 for SI in predicting 24-hour mortality. There was significant difference between the diagnostic performances of 2 markers in predicting 24-hour mortality. AUC was found to be 0.775 for lactate and 0.722 for SI in predicting 28-day mortality. No significant difference was found between the diagnostic performances of the two markers in predicting 28-day mortality. The 24-hour non-survivor rates were found to be 86.67% in patients with lactate levels >2.57; 76.47% in patients with SI >0.94, and 93.33% in patients with lactate levels >2.57 or SI >0.94. The 28-day non-survivor rates were found to be 64.71% in patients with lactate levels >2.57; 70.59% in patients with SI >0.82, and 82.35% in patients with lactate levels >2.57 or SI >0.82.

CONCLUSION

Lactate level and SI of AHF patients calculated in ED triage may be used to predict mortality, and simultaneous use of both parameters may be more helpful. Key Words: Acute heart failure, Emergency department, Lactate, Mortality, Shock index.

摘要

目的

比较休克指数(SI)和乳酸在预测急性心力衰竭(AHF)患者24小时和28天死亡率方面的效用。

研究设计

一项描述性研究。研究地点和时间:土耳其巴勒克埃西尔的巴勒克埃西尔大学医院;2019年2月至2020年8月。

方法

招募112名到急诊科就诊的AHF患者纳入研究。评估乳酸和SI在预测24小时和28天死亡率方面的效用。

结果

在预测24小时死亡率方面,乳酸的曲线下面积(AUC)为0.825,SI为0.818。两种标志物在预测24小时死亡率的诊断性能上存在显著差异。在预测28天死亡率方面,乳酸的AUC为0.775,SI为0.722。两种标志物在预测28天死亡率的诊断性能上未发现显著差异。乳酸水平>2.57的患者24小时非生存率为86.67%;SI>0.94的患者为76.47%,乳酸水平>2.57或SI>0.94的患者为93.33%。乳酸水平>2.57的患者28天非生存率为64.71%;SI>0.82的患者为70.59%,乳酸水平>2.57或SI>0.82的患者为82.35%。

结论

在急诊科分诊时计算的AHF患者的乳酸水平和SI可用于预测死亡率,同时使用这两个参数可能更有帮助。关键词:急性心力衰竭;急诊科;乳酸;死亡率;休克指数。

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