Uzunoglu Hakan, Kaya Selcuk
Department of General Surgery, Kartal Dr Lütfi Kirdar City Hospital, Istanbul, Turkey.
J Coll Physicians Surg Pak. 2021 Mar;31(3):288-293. doi: 10.29271/jcpsp.2021.03.288.
To investigate the prognostic value of tumor diameter in the short term of 3 and 5 years in patients operated for gastric cancer.
A descriptive study.
Kartal Dr Lütfi Kırdar City Hospital, Istanbul, Turkey, from January 2014 to December 2018 Methodology: A total of 125 patients with stage 2 or 3 gastric cancer, followed up in the Department of General Surgery, were included. Demographic information, clinical, laboratory, and pathology reports were analysed in terms of postoperative 30-day mortality.
The mean age of the patients was 63.9±11.9 (31-88) years. Forty-four (35.2%) were in stage 2, and 81 (64.8%) were in stage 3 cancers. The mean tumor diameter was 6.5±3.1 cm, and the mean metastatic lymph node rate was 35.6±29.8%. The mean follow-up period was 31.8±21 months. The 3-year and 5-year survival rates were 39.8% and 17.6%, respectively. Tumor diameter was not directly related to survival, differentiation, number of resected lymph nodes, number of metastatic lymph nodes, and metastatic lymph node rate in stage 2 and 3 cases (p>0.05 for each). The 5-year mortality risk was 1.2-fold higher in those with tumor diameter over 6.5 cm (95% CI 0.7-2.0; p=536).
The tumor size did not have a direct effect on prognosis. It did not provide reliable data about short-term prognosis such as 3 and 5 years in stage 2 and 3 gastric cancer cases. Key Words: Gastric cancer, Stage 2, Stage 3, Tumor size, Prognosis.
探讨肿瘤直径对接受胃癌手术患者3年和5年短期预后的价值。
描述性研究。
土耳其伊斯坦布尔的卡尔塔尔·吕特菲·基尔达尔市立医院,2014年1月至2018年12月
纳入普外科随访的125例2期或3期胃癌患者。分析人口统计学信息、临床、实验室和病理报告的术后30天死亡率。
患者的平均年龄为63.9±11.9(31 - 88)岁。44例(35.2%)为2期,81例(64.8%)为3期癌症。平均肿瘤直径为6.5±3.1 cm,平均转移淋巴结率为35.6±29.8%。平均随访期为31.8±21个月。3年和5年生存率分别为39.8%和17.6%。在2期和3期病例中,肿瘤直径与生存率、分化程度、切除淋巴结数量、转移淋巴结数量及转移淋巴结率均无直接关系(每项p>0.05)。肿瘤直径超过6.5 cm者5年死亡风险高1.2倍(95%CI 0.7 - 2.0;p = 0.536)。
肿瘤大小对预后无直接影响。它不能为2期和3期胃癌病例的3年和5年等短期预后提供可靠数据。
胃癌;2期;3期;肿瘤大小;预后