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宫颈高级别鳞状上皮内病变累及子宫内膜及子宫腺肌病:一例报告及文献复习

Cervical HSIL Involving the Endometrium and Adenomyosis: A Case Report and Literature Review.

作者信息

Wang Wenwen, Zhou Feng

机构信息

Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.

出版信息

J Coll Physicians Surg Pak. 2021 Mar;31(3):337-339. doi: 10.29271/jcpsp.2021.03.337.

DOI:10.29271/jcpsp.2021.03.337
PMID:33775028
Abstract

Cervical squamous cell carcinoma (SCC) spreading superficially to the inner surface of the uterus and replacing the endometrial lining cells with carcinoma cells is called superficial spreading SCC. We, hereby report a 53-year postmenopausal woman who had a history of cervical SCC in situ/high grade squamous intraepithelial lesion (HSIL). Ultrasonography revealed an enlarged uterus measuring 9.0×6.5×5.0 cm with dilatation of the uterine cavity and the cervical canal. Subsequently, she underwent total abdominal hysterectomy (TAH) and bilateral salpingo-ophorectomy with a diagnosis of cervical HSIL involving the endometrium and adenomyosis. This a very rare phenomenon, as the endometrial involvement may be caused by direct extension of the cervical lesion, and occur mainly in postmenopausal women, and should be deligently searched during pathological examination. Key Words: HSIL, Cervix, Endometrium, Adenomyosis.

摘要

宫颈鳞状细胞癌(SCC)向子宫内表面浅表扩散,并用癌细胞取代子宫内膜衬里细胞,称为浅表扩散性SCC。在此,我们报告一名53岁的绝经后妇女,她有宫颈原位SCC/高级别鳞状上皮内病变(HSIL)病史。超声检查显示子宫增大,大小为9.0×6.5×5.0 cm,宫腔和宫颈管扩张。随后,她接受了全腹子宫切除术(TAH)和双侧输卵管卵巢切除术,诊断为累及子宫内膜和子宫腺肌病的宫颈HSIL。这是一种非常罕见的现象,因为子宫内膜受累可能是由宫颈病变直接蔓延引起的,主要发生在绝经后妇女中,在病理检查时应仔细查找。关键词:HSIL、宫颈、子宫内膜、子宫腺肌病。

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引用本文的文献

1
Superficial spreading squamous cell carcinoma of the cervix involving the endometrium: A case report and literature review.宫颈浅表扩散性鳞状细胞癌累及子宫内膜:一例报告及文献复习
Exp Ther Med. 2025 Aug 5;30(4):185. doi: 10.3892/etm.2025.12935. eCollection 2025 Oct.
2
An unusual pattern of endometrial involvement: superficial spreading squamous cell carcinoma of the cervix.一种不寻常的子宫内膜受累模式:宫颈浅表播散性鳞状细胞癌。
Front Oncol. 2024 Oct 1;14:1456297. doi: 10.3389/fonc.2024.1456297. eCollection 2024.
3
Endometrial squamous cell carcinoma originating from the cervix: A case report.
起源于宫颈的子宫内膜鳞状细胞癌:一例报告。
World J Clin Cases. 2022 Aug 26;10(24):8782-8787. doi: 10.12998/wjcc.v10.i24.8782.