Goldminz D, Barnhill R, McGuire J, Stenn K S
Department of Dermatology, Yale University School of Medicine, New Haven, Conn. 06510-8059.
Arch Dermatol. 1988 Jun;124(6):922-5.
A 27-year-old woman with hypoparathyroidism developed multiple firm white-yellow papules along the path of an infiltrated calcium chloride intravenous infusion. A biopsy specimen obtained ten days after the extravasation revealed an urticarial reaction. A subsequent biopsy specimen, obtained 25 days after the extravasation, showed diffuse dermal calcification, confirmed by roentgenographic analysis, with incipient transepidermal elimination. A biopsy specimen obtained 40 days after the extravasation was consistent with an elimination reaction. An increase in mast cells was not noted. Electron microscopy showed mineral deposits along collagen fibrils without significant collagenous degeneration. In this report we describe a complication of intravenous calcium chloride infusion.
一名患有甲状旁腺功能减退症的27岁女性，在氯化钙静脉输注渗入的路径上出现了多个坚实的白黄色丘疹。外渗十天后获取的活检标本显示为荨麻疹反应。外渗25天后获取的后续活检标本显示有弥漫性真皮钙化，经X线分析证实，伴有早期经表皮排出。外渗40天后获取的活检标本符合排出反应。未观察到肥大细胞增多。电子显微镜检查显示矿物质沉积于胶原纤维周围，无明显的胶原变性。在本报告中，我们描述了氯化钙静脉输注的一种并发症。
