Puvabanditsin Surasak, Garrow Eugene, Titapiwatanakun Ruetima, Getachew Rahel, Patel Jigneshkumar B
Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
Pediatr Radiol. 2005 May;35(5):539-42. doi: 10.1007/s00247-004-1363-9. Epub 2004 Nov 23.
We report on an infant with severe asphyxia and persistent pulmonary hypertension as a newborn. The baby received prolonged intravenous calcium gluconate therapy for hypocalcemia. At 5 weeks of age, multiple firm, indurated areas (armor-like lesions) were palpable in the subcutaneous tissues of the trunk, arms, legs, and face, particularly in skin folds. Roentgenographic study showed generalized soft-tissue calcifications throughout the body, extremities, and face. Calcinosis cutis occurs through a variety of pathogenetic mechanisms. Case reports on calcinosis cutis in infants are uncommon, and the calcifications are mostly localized. In our patient, they are generalized.
我们报告一例新生儿期患有严重窒息和持续性肺动脉高压的婴儿。该婴儿因低钙血症接受了长时间的静脉注射葡萄糖酸钙治疗。在5周龄时,在躯干、手臂、腿部和面部的皮下组织中可触及多个坚硬、硬结的区域(铠甲样病变),尤其是在皮肤褶皱处。X线检查显示全身、四肢和面部均有广泛性软组织钙化。皮肤钙化症可通过多种发病机制发生。关于婴儿皮肤钙化症的病例报告并不常见,且钙化大多为局限性。在我们的患者中,钙化是全身性的。